Protein Alignment CG43066 and SLC6A11

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_055044.1
• Gene: SLC6A11 / 6538
• HGNCID: 11044
• Length: 632
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 197/586 - (33%)
• Similarity: 301/586 - (51%)
• Gaps: 94/586 - (16%)

  Fly    54 ERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQR 118
            ||..|:.|::|.||:.|..:||||:|||||||.:|||||||||::|..|..|||:|.:|..:||.
Human    49 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQF 113

  Fly   119 MRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLNGTGF 183
            ...|.:..|..:.|...|||.::.::...:.:||.:|:.|..|||.|.|...|||::|   |..:
Human   114 TSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATC---GHEW 175

  Fly   184 ELEECAK-----------------SSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVF 231
            ..|.|.:                 :|....||....|..:..::..|.|:|.:.|||:.:|||.:
Human   176 NTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY 240

  Fly   232 FIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQ 296
            |.:.||.:|:|||||.|:.||||:|.|..|||:||.||..|:.....|.:.:|.:|.||:||.||
Human   241 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQ 305

  Fly   297 VFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVAS 361
            :|:|:.:..|.|.|.||||...|||.||.:::...|:.|:..|...||::|||.|
Human   306 IFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA---------- 360

  Fly   362 NTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVE 426
                              |||.:.:                   .:.|..|.|||||.:.:|:..
Human   361 ------------------YEQGVPI-------------------AEVAESGPGLAFIAYPKAVTM 388

  Fly   427 LPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDI--DIIKR-VKKQHVTGVVCLFCFIVGFI 488
            :|.:|.||.|||.||:.|||.||...:|.::..:.|:  .:.:| .:::.:...:.:..:.:|.:
Human   389 MPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLV 453

  Fly   489 FCTGAGEYWLKMFDSFAGT-IGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRY 552
            ..|..|.|..::|||:|.: :.|:.||:.|.|.:.::||..||.::|..|.||||....:|.|..
Human   454 MLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMI 518

  Fly   553 IGPVIMVCILVSSVVFMVIR------NPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMP 611
            :.|.|...|.    :|.:|:      |..|             :||.|..||...|.|:.:|.:|
Human   519 MTPGICAGIF----IFFLIKYKPLKYNNIY-------------TYPAWGYGIGWLMALSSMLCIP 566

  Fly   612 I 612
            :
Human   567 L 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	196/585 (34%)
SLC6A11	NP_055044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		SLC6sbd_GAT3	49..590	CDD:212077	197/586 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810