Protein Alignment CG43066 and SLC6A7

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_016865256.1
• Gene: SLC6A7 / 6534
• HGNCID: 11054
• Length: 754
• Species: Homo sapiens
• Alignment Length: 760
• Identity: 250/760 - (32%)
• Similarity: 362/760 - (47%)
• Gaps: 192/760 - (25%)

  Fly    13 GHEMAPLNTRARGDGTH---GVT--IVLTAPQRNSVQ-SVDIPGNEPERAAWSGKMQFFLSIIGY 71
            ||   ||:...:..|.|   .||  :::|...:..|. .||...:   |..|:||:.|.||.|||
Human    76 GH---PLSKMKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAAH---RGNWTGKLDFLLSCIGY 134

  Fly    72 SVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGG 136
            .|||||:|||||....|||||||:|:.:||.:.|||||.:||.:||...||.|.||. |.|...|
Human   135 CVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWK-ISPLFKG 198

  Fly   137 IGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC----------------------PLN 179
            .|.:..::...||:|||:||.:|.||||.|....|||..|                      |||
Human   199 AGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALPLN 263

  Fly   180 GTGFELEECAKSSETTYFWYRTTLDA----------------------APSMDE----------- 211
            .|      |..|....| |.:|..:|                      .|..:|
Human   264 LT------CTVSPSEEY-WSQTHTEAEEEGRRGRVVSNSYPQVIFLPQPPKAEEGVSRYVLHIQG 321

  Fly   212 ------PGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAG 270
                  ||.::|.:.|||:|:|.|||..::||::|||||||||:.|||::|.:..:||:||.||.
Human   322 SQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAW 386

  Fly   271 AGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVT 335
            .|:....||:...||...||::||.|:|||.|:.||.|:.|.||||...|..||..:|::.||:|
Human   387 KGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAIT 451

  Fly   336 AIYASVVIFAILGFKAT---VNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQL 397
            :|.|...||::||:.:.   |.||:.
Human   452 SILAGFAIFSVLGYMSQELGVPVDQV--------------------------------------- 477

  Fly   398 SECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFD 462
                       |..|.||||:|:.||:..||.:|||:.|||.|||:|||.||...||.::..:.|
Human   478 -----------AKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTD 531

  Fly   463 -IDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYG 526
             .....|.||...:|::|:..:::|.|..|..|.|||.:.|.::.:.||:||.:...:||..:||
Human   532 EFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYG 596

  Fly   527 HERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSY 591
            .:||..||..|.|::||.|::..|.::.|..::.::|.|:|  ..:...||::.          :
Human   597 IQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIV--KYQPSEYGSYR----------F 649

  Fly   592 PNW--VMGIALS-----MILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEMIDND 649
            |.|  ::||.:.     ||.||:|    |.::|           .:||:......||...|
Human   650 PPWAELLGILMGLLSCLMIPAGML----VAVLR-----------EEGSLWERLQQASRPAM---- 695

  Fly   650 DDDDEDDENDFSGPAL-----GGHVKTQSDFSDDDEEDKPMTMRM 689
                     |: ||:|     |.:|.|.:    ..:..||:.:.|
Human   696 ---------DW-GPSLEENRTGMYVATLA----GSQSPKPLMVHM 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	222/633 (35%)
SLC6A7	XP_016865256.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810