Protein Alignment CG43066 and slc6a16b

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001103944.1
• Gene: slc6a16b / 567809
• ZFINID: ZDB-GENE-070424-95
• Length: 676
• Species: Danio rerio
• Alignment Length: 663
• Identity: 271/663 - (40%)
• Similarity: 382/663 - (57%)
• Gaps: 70/663 - (10%)

  Fly    50 GNEPE------RAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPL 108
            |.|||      |..|..|:::||:.:|:||||||:|||||||.|||||||::.::|::.|.|:||
Zfish    22 GLEPEVPLETARDGWDSKVEYFLAQVGFSVGLGNVWRFPYLCHQNGGGAFILLYVVLMALVGVPL 86

  Fly   109 FLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPW 173
            |.:||..||.:|.|::|||..|.|.|.|||.|||:|..||||||||||.|..|||.|||:|||||
Zfish    87 FFLELAAGQSIRQGSIGVWRHISPKLVGIGYSSCVVCFFVALYYNVIIGWSIFYLGNSFQYPLPW 151

  Fly   174 SSCPLNGTGFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGI 238
            ..||..|.. .::|||.||.|.|||||..||...|:||.|...:.:..||:.:|.||...:.|||
Zfish   152 EKCPTEGNS-TVKECAASSPTAYFWYRKALDITDSIDETGEFNFILTGCLLAAWVIVCLAMYKGI 215

  Fly   239 QSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGL 303
            :|||||:||:|:|||:||..|.|||:||.||..|:..|:.|::|...:..||..||||||::.||
Zfish   216 KSSGKVMYFSSVFPYVVLLCFLIRGVTLDGASEGIKFMFYPRLEIWADVQVWRQAATQVFFALGL 280

  Fly   304 AFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVK 368
            .|||:||:.|||...|||.||...||..|.:|::.|::|:||:|||:|......||..|.:.|:|
Zfish   281 GFGSVIAYSSYNPRNNNCHRDAFTVSGVNFMTSVLATLVVFAVLGFRAKTIAAECVKRNLKALLK 345

  Fly   369 ------NKLLGLN----------------DTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAE 411
                  ..:|.:|                .|||.|.::|..|        ::.|||..||....|
Zfish   346 VTSSAPLPVLSINASDVESISLDEYANWYSTQGMELSISDYN--------ITACSLEDELRQGVE 402

  Fly   412 GTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTG 476
            .||||||.||:|:...||:|||:.|||.|||:|||.:..|.:.|:|..|.|.....|..|...|.
Zfish   403 ETGLAFIAFTEAMTLFPGSPFWSALFFLMLLNLGLSTMFGTMAGILTPLTDTFKTLRNHKLIFTI 467

  Fly   477 VVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYR 541
            ..|...|::|.:|....|.|::.|||.::.|:.|::|.:.:.|:|.::||.:||.||:.||....
Zfish   468 CSCTVGFVIGLVFTQRCGNYFVTMFDDYSATLPLIIVVIFQTISVSWVYGADRFLEDLKQMLNRP 532

  Fly   542 PGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAG 606
            ....:::.|:::.|:.|:.:|.:|::.|:::.|.|.|||.:....|...||:|.:.:.:.:|:..
Zfish   533 VPVIYKYLWKFVCPIAMLGLLGASLLKMILKRPEYSAWNREKASKEDLPYPDWALAVLIILIIIA 597

  Fly   607 VLPMPIVFL----------------MRSFQCLKVDLDIHQGSIRRNETTASTKEMIDNDDDDDED 655
            .||:||.::                .|...|...|.|:         |..||.       ....|
Zfish   598 SLPVPIGYIHSLLLERLGQSPADTEARYTPCATTDTDL---------TPLSTL-------PPSRD 646

  Fly   656 DENDFSGPALGGH 668
            |.|. |.|.|.|:
Zfish   647 DLNS-SHPLLEGN 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	253/599 (42%)
slc6a16b	NP_001103944.1	SLC6sbd-B0AT-like	33..607	CDD:271364	253/582 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	581	1.000	Domainoid score	I204
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	589	1.000	Inparanoid score	I948
OMA	1	1.010	-	-		QHG48419
OrthoDB	1	1.010	-	-		D251682at33208
OrthoFinder	1	1.000	-	-		FOG0001784
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101967
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.980