Protein Alignment CG43066 and slc6a22.2

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_005166102.1
• Gene: slc6a22.2 / 561024
• ZFINID: ZDB-GENE-030616-628
• Length: 608
• Species: Danio rerio
• Alignment Length: 584
• Identity: 195/584 - (33%)
• Similarity: 305/584 - (52%)
• Gaps: 81/584 - (13%)

  Fly    53 PERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQ 117
            |.|..|:.|::|.|::.|:.:||||:|||||||.:||||||.:|:::.|...|||||.:|..:||
Zfish    26 PAREQWANKLEFLLAVAGHIIGLGNVWRFPYLCYKNGGGAFFVPYVLFLFTCGIPLFFLETSLGQ 90

  Fly   118 RMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLNGTG 182
            ....|.:..|..|.|...|:|..|.:|.|:..:||.:|:.|.|.|||:||...|||:||   ...
Zfish    91 FTSQGGITCWRKICPLFEGLGFGSQVVVLYTGVYYIIILAWAFLYLFSSFTSELPWASC---NNY 152

  Fly   183 FELEECAKSSE---TTY-----------FWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFI 233
            :....|.:.||   |.|           ||.|..|..:..:::.|.::|.:.|||:|:|.|.:|.
Zfish   153 WNTPSCMEFSESNITEYSPNKTTSPVIEFWERRILGLSGGIEQIGNVRWDLALCLLLAWIICYFC 217

  Fly   234 VMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVF 298
            |.||::|:|||||||:.|||::|.:..:||:||.||..|:.....|...:|.:|.||:||.:|:|
Zfish   218 VWKGVKSTGKVVYFTATFPYLMLIVLLVRGLTLPGAINGITFYLYPDPSRLKDPQVWMDAGSQIF 282

  Fly   299 YSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNT 363
            ||:|:..|.|.|.||||...|||.||.:.:.:.|::|:..|...||::|||.|
Zfish   283 YSYGVCTGVLTALGSYNKYDNNCYRDCVYLCLLNSLTSFVAGFAIFSVLGFMA------------ 335

  Fly   364 EILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELP 428
                        |.||.:  :||:                     |..|.|||||.:.:|:..:|
Zfish   336 ------------DEQGVD--ISLV---------------------AESGPGLAFIAYPRAVALMP 365

  Fly   429 GAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDI-DIIKRV--KKQHVTGVVCLFCFIVGFIFC 490
            ....||:.||.|::.|||.|:....|.::.::.|: ....:|  :::.:...:|...|.||.:..
Zfish   366 LPQLWAIFFFIMIIFLGLDSEFVYQEALVTSISDMYPSFFQVGHRRKFLLLFICSASFFVGLLMV 430

  Fly   491 TGAGEYWLKMFDSFA-GTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIG 554
            |..|.|..::||.:| ..:.|:..|:::.|.|.::||.:|..:.:..|.||||..:.:..|:|:.
Zfish   431 TEGGLYVFQLFDYYACSGMTLLTFAILQSICVGWVYGADRHYDCVEDMIGYRPWPFMKCCWKYLT 495

  Fly   555 PVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPI--VFLM 616
            |.|.....:.|:|       .|    ..|....:..||.|...|.....|:..|.:|:  ::|:
Zfish   496 PAICTGTFIFSLV-------QY----TPLKFNNEYEYPWWGYAIGGFFTLSSTLLVPLWMIYLV 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	194/582 (33%)
slc6a22.2	XP_005166102.1	SLC6sbd-TauT-like	28..565	CDD:271387	194/582 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810