Protein Alignment CG43066 and slc6a6a

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001119858.1
• Gene: slc6a6a / 556480
• ZFINID: ZDB-GENE-081104-1
• Length: 625
• Species: Danio rerio
• Alignment Length: 594
• Identity: 203/594 - (34%)
• Similarity: 316/594 - (53%)
• Gaps: 85/594 - (14%)

  Fly    50 GNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELG 114
            |..|:|..|:.|:.|.||:.|..|||||:|||||||.:|||||||||:.:.|...|:|:|.:|:.
Zfish    36 GKAPQREKWASKLDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVA 100

  Fly   115 IGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLN 179
            :||....|.:..|..:.|...|||.:|.|:...:.:||.||:.|..:||...|::.|||:.|
Zfish   101 LGQFTSEGGITCWGKLCPIFTGIGYASIIIVSLLNIYYIVILAWGLYYLLQCFQHELPWARC--- 162

  Fly   180 GTGFELEECAK------------------SSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLS 226
            ...:..|.|.:                  :|..|.||.|..|..:..:||.|||||.:.|||:..
Zfish   163 RHSWNTENCVEDTVRKNKTLWLSANATNFTSPVTEFWERNVLSISSGIDEVGGLKWELALCLLAV 227

  Fly   227 WTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWL 291
            |.|.||.:.||::|:|||||||:.||:::|.:..|||:||.||..|:.....|.:.:|.:|.||:
Zfish   228 WVICFFCIWKGVKSTGKVVYFTATFPFLMLIVLLIRGVTLPGATEGIKFYLYPDLSRLKDPEVWI 292

  Fly   292 DAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVD 356
            ||.||:|:|:.:..|::.:.||||..|.||.||.:|:...|:.|:..:...||::|||.|
Zfish   293 DAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGFAIFSVLGFMA----- 352

  Fly   357 RCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFT 421
                                   .||.:::                   .|.|..|.|||||.:.
Zfish   353 -----------------------QEQGIAI-------------------ADVAESGPGLAFIAYP 375

  Fly   422 QAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDID---IIKRVKKQHVTGVVCLFCF 483
            :|:..:|....||:|||.|||.|||.||...:||.:.:|.|:.   :.|..:::....|:|:..:
Zfish   376 KAVTMMPLPTVWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSLLRKGYRREIFIAVICVISY 440

  Fly   484 IVGFIFCTGAGEYWLKMFDSFAGT-IGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQ 547
            ::|....|..|.|..::||.:|.: :.|:.||..|.:||.::||.:.|.:.|..|.||||..:.:
Zfish   441 LLGLTMVTKGGMYVFQLFDYYAASGVCLLWVAFFECVAVAWVYGADNFYDAIEDMIGYRPNSWMK 505

  Fly   548 WTWRYIGPVIMV-CILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMP 611
            |:|..|.||:.| |.:.|.|.:..:   ||.         :...||:|.:|:..::.||.::.:|
Zfish   506 WSWMLITPVLCVGCFVFSLVKYKPL---TYN---------KLYKYPDWSIGLGWALALASMICIP 558

  Fly   612 IVFLMRSFQ 620
            ::.:::..|
Zfish   559 MMVVIKIIQ 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	200/584 (34%)
slc6a6a	NP_001119858.1	SLC6sbd_TauT	41..582	CDD:271398	201/589 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910