Protein Alignment CG43066 and slc6a1b

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 645
• Identity: 223/645 - (34%)
• Similarity: 342/645 - (53%)
• Gaps: 87/645 - (13%)

  Fly    16 MAPLNTRARGDGTHGVTIVLTAPQRNS-----VQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGL 75
            ||...|:| .|| |.:|.|..||..|.     |..|......|:|..|.||..|.||.:||::||
Zfish     1 MATNGTKA-SDG-HVLTEVNEAPTANDKPKTLVVKVQKKKELPDRETWQGKFDFLLSCVGYAIGL 63

  Fly    76 GNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGIS 140
            ||:|||||||.:|||||||||:.:.||..|:|||.:|..:||...:|.||||. :.|...|:|::
Zfish    64 GNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLETALGQYTSIGGLGVWK-LAPMFKGVGLA 127

  Fly   141 SCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC--PLNGTGFELEECAK----------SSE 193
            :.:::.::.:||.|||.|..:||:|||...|||.||  |.|     .::|..          :|.
Zfish   128 AAVLSFWLNIYYIVIIAWAIYYLYNSFTTDLPWKSCDNPWN-----TDKCFSNYSMANIGNMTSA 187

  Fly   194 TTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTI 258
            ...||.|........:::||.::..:.:.|.::|.:|:|.:.||:..:||||||::.:||.:|.|
Zfish   188 VVEFWERNMHQLTDGLEKPGEIRLPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYFMLFI 252

  Fly   259 FFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVR 323
            .||||:||.||..|::...||:..||.|..||||||||:|:|:||..|||||.||||...||..:
Zfish   253 LFIRGVTLPGAKEGILFYVTPEFSKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYK 317

  Fly   324 DVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLN 388
            |.::|...|:.|:::|..|||:|:||.|.: ..|.:|
Zfish   318 DSIIVCCINSFTSMFAGFVIFSIVGFMAHI-TKRPIA---------------------------- 353

  Fly   389 GTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGIL 453
                              |.||.|.||||:.:.:|:.:||.:|.||||||:|||.||:.||...:
Zfish   354 ------------------DVAASGPGLAFLAYPEAVTQLPISPLWAVLFFSMLLMLGIDSQFCTV 400

  Fly   454 EGMLCTLFD-IDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSF-AGTIGLVVVALM 516
            ||.:..|.| .....|.:::....||||..:::|....|..|.|..|:||.: |..:.|:.:...
Zfish   401 EGFITALVDEFPRALRGRREIFIAVVCLVSYLIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFF 465

  Fly   517 EMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMV---IRNPTYGA 578
            |.:::.:.||..:|..::.:|.||:|..:|:..|....|:|:..:.:.|.|.||   :.|..:..
Zfish   466 ECVSISWFYGVNKFYGNLEEMIGYKPCIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTLNNYVFPK 530

  Fly   579 WNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMRSF-QCLKVDLDIHQGSIRRNE 637
            |...:|         |.|.::..:::.|.:....:.|..|: :.|::.:.....::|..|
Zfish   531 WGQGVG---------WCMALSSMVLIPGYMGYMFLTLKGSYKERLRIMIQPTAAAVRTQE 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	204/578 (35%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:294310	222/644 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810