Protein Alignment CG43066 and Slc6a16

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001311464.1
• Gene: Slc6a16 / 381884
• MGIID: 2685930
• Length: 742
• Species: Mus musculus
• Alignment Length: 649
• Identity: 190/649 - (29%)
• Similarity: 325/649 - (50%)
• Gaps: 45/649 - (6%)

  Fly    34 VLTAPQRNS--VQSVDIPGNE--PERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFL 94
            |.|..|.:|  |..:....:|  |.|..|:.|:::.|:|:.|.:....:.||.......|..:|.
Mouse   100 VTTLEQESSELVNRMSRESSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFF 164

  Fly    95 IPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWV 159
            |.:::||:..||||..:|:.:|||.:..:..:|..:.||.||:|.|..:|......|.||..:|:
Mouse   165 IAYILMLLGIGIPLLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFNSWI 229

  Fly   160 FFYLFNSFRYPLPWSSCPL--NGTGFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLC 222
            .||:.:.|.:.:||..|||  |.:.|: .||.:::..||||||.||.|:..:::.|...:.:.:.
Mouse   230 LFYMSHIFYFVVPWDQCPLQRNSSNFD-PECEQATSYTYFWYRKTLKASDRIEDGGQPSFSLGMS 293

  Fly   223 LMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEP 287
            |.||:.::...::.||:|.|||::...|.||.::..|.||.:::.||..||.|:...||..:.:.
Mouse   294 LFLSFCLICAFLVNGIKSIGKVLFVLLLVPYSIIVCFLIRTLSMDGAEYGLKHLLILKVASISDL 358

  Fly   288 TVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKAT 352
            |:|..|..||.:..||.||.:::..|:....|||:.|..|:::...:|.:..:..:.:||||.||
Mouse   359 TIWCHAGIQVLFDIGLGFGPIVSLASHVPDFNNCMADAFLMALFKIITLLMTTPFLLSILGFWAT 423

  Fly   353 VNVDRCVASNTEILVKNKLLGL------------NDTQGYEQAMSLLNGTELLRLQLS---ECSL 402
            .....|...|.|.|::....|:            |.|..|...:|.| ...|....||   |||:
Mouse   424 TTTHHCCKKNQETLLRLVAQGILPPDAQPPDLSGNPTSNYNSWLSSL-PPPLRSAVLSVVPECSV 487

  Fly   403 AHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIK 467
            ..:.....:.....|::||:.|..|||:.||.||||.:||:|||.|.:..:.|.:.||.|.....
Mouse   488 QKQFLKIKDNPRFLFLIFTEVISLLPGSGFWIVLFFLLLLTLGLCSNLMFMLGNVLTLQDTFPFC 552

  Fly   468 RVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTE 532
            |.:.:.:...|.:..|:.|.||...:|.|:..:.......:.::::.:.|.:||.:.||.:||..
Mouse   553 RRQPRLLIVCVSMAMFLCGLIFIQPSGIYYFSLLSECWVAVPVIIIIICENLAVAWAYGADRFLA 617

  Fly   533 DIFQMTGYRP-----GRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYP 592
            |:..:.| ||     |    |.|.||.|::::.:|.|..|::|.....|.||::.......:.:|
Mouse   618 DMVALLG-RPIFSGCG----WLWCYISPMVVLGLLTSVFVYLVKGPLVYFAWDSSTSKEVVRVFP 677

  Fly   593 NWVMGIALSMILAGVLPMPIVFL--------MRSFQCLKVDLDIHQGSIRRNETTASTKEMIDN 648
            .|...:...:.:..::|:|..|:        .||....|:.|    ||.:...|..::|:::.:
Mouse   678 EWSKILIAGLTVFVLMPIPAYFVYCLTLGIPFRSTPSSKLPL----GSGQLQSTKEASKDILQD 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	175/591 (30%)
Slc6a16	NP_001311464.1	SLC5-6-like_sbd	125..694	CDD:294310	172/575 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010