Protein Alignment CG43066 and slc6a22.1

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_005166076.1
• Gene: slc6a22.1 / 368923
• ZFINID: ZDB-GENE-030616-629
• Length: 584
• Species: Danio rerio
• Alignment Length: 577
• Identity: 200/577 - (34%)
• Similarity: 307/577 - (53%)
• Gaps: 79/577 - (13%)

  Fly    55 RAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRM 119
            |..||.|::|.|::.|..:||||:|||||||.:||||.|.||::|.|...||||||:|..:||..
Zfish    30 RGQWSSKVEFILAVAGQIIGLGNVWRFPYLCYKNGGGVFFIPYVVFLFACGIPLFLMETALGQYT 94

  Fly   120 RLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC-----PLN 179
            ..|::..|..|.|...|:|..|.:|.|:.:.||.:|:.|.|||||:||...|||:||     ..|
Zfish    95 SQGSVTCWRKICPLFEGLGYGSQVVVLYSSAYYIIILAWAFFYLFSSFSGELPWASCRNWWNSEN 159

  Fly   180 GTGFELEECAK--------SSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMK 236
            ...|:..:.||        ||....||.|..|:...|::|.|.::|.:.|||:|:|.|.:|.|.|
Zfish   160 CVEFDRMQGAKNLSFMANASSPVKEFWERRVLNITGSVNELGSVRWELALCLLLAWVICYFCVWK 224

  Fly   237 GIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSF 301
            |::|:|||||||:.|||::|.:..|||:||.||..|:.....|...:|.:|.||:||.||:|||:
Zfish   225 GVKSTGKVVYFTATFPYVMLMVLLIRGLTLPGAIDGITFYLYPNPARLADPQVWMDAGTQIFYSY 289

  Fly   302 GLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEIL 366
            .|..|.|.|.||||...|||.:|.:.:.:.|:.|:..|...||::|||
Zfish   290 ALCIGCLTALGSYNKYNNNCYKDCVYLCLLNSGTSFVAGFAIFSVLGF----------------- 337

  Fly   367 VKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAP 431
                             |:|..|.::..:             |..|.|||||.:.:|:..:|.|.
Zfish   338 -----------------MALEQGVDISVV-------------AESGPGLAFIAYPRAVAMMPMAQ 372

  Fly   432 FWAVLFFTMLLSLGLGSQIGILEGMLCTLFDID---IIKRVKKQHVTGVVCLFCFIVGFIFCTGA 493
            .|::.||.|::.|||.|:...||.::..:.|::   .::..:::....|:|:.||::|.:..|..
Zfish   373 LWSICFFLMIILLGLDSEFVGLESLMTAITDMNPNFFLQGHRRKLFLLVICIACFLIGLLMVTEG 437

  Fly   494 GEYWLKMFDSFA-GTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVI 557
            |.|..::||.:: ..:.|::.|:.:.|.:.:.||.:|..|:|..|.||.|....::.|:||.|::
Zfish   438 GLYVFQLFDYYSCSGMTLLLFAIAQSICIGWFYGADRLYENIADMIGYHPLTLMKYCWKYITPIV 502

  Fly   558 MVCILVSSVV-FMVIR-NPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPI 612
            .:...:.|:| |..:: |.||             .||.|.........|:..|.:||
Zfish   503 CIGTFIFSLVKFTPLKFNNTY-------------EYPWWGYAAGWWFTLSSTLLVPI 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	200/577 (35%)
slc6a22.1	XP_005166076.1	SLC6sbd-TauT-like	30..569	CDD:271387	200/577 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810