Protein Alignment CG43066 and DAT

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 661
• Identity: 231/661 - (34%)
• Similarity: 327/661 - (49%)
• Gaps: 136/661 - (20%)

  Fly    38 PQRNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLI 102
            |..|...|:     ..||..||||:.|.||:||::|.|.|:|||||||.:|||||||:|:.:||:
  Fly    15 PHDNDNNSI-----SDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLV 74

  Fly   103 LEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSF 167
            :.|||||.:||.:||..|.||:..|..:.|...|||.:..::..:|..||||||.|...:.|.||
  Fly    75 VGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASF 139

  Fly   168 RYPLPWSSCP------------------------------------------LNGTGFELE---- 186
            ...|||:||.                                          :||:..:..
  Fly   140 TNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGH 204

  Fly   187 -ECAKSSETTYF-WYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTS 249
             |..:|:.:.|| .|...|:.:..:.:.|.:||.:.|||::.:.|.:|.:.|||.:|||||:||:
  Fly   205 VEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTA 269

  Fly   250 LFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSY 314
            ||||.||.|..|||:||.|:..|:.:..||....:.:..||:|||||||:|.|..||.|:|:.||
  Fly   270 LFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASY 334

  Fly   315 NTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQG 379
            |...||..:|.||.|..|:.|:..|..|||::||:
  Fly   335 NKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGY------------------------------ 369

  Fly   380 YEQAMSLLNGTELLRLQLSECSLAHEL-----DNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFT 439
                                  :||.|     |.|.||.||.|:|:..||..:|.:.|||::||.
  Fly   370 ----------------------MAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFM 412

  Fly   440 MLLSLGLGSQIGILEGMLCTLFD-IDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDS 503
            |||:|||.|..|..|.::..|.| ...|||.::..|.|:..|: |:||...||..|.|:..:.|.
  Fly   413 MLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLY-FVVGLASCTQGGFYFFHLLDR 476

  Fly   504 FAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVF 568
            :|....::|....|.|||.:|||..||:|||..|.|:.||||||..||::.|:.::.|.|
  Fly   477 YAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITV----- 536

  Fly   569 MVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAG--VLPMPIVFLMRSFQCLKVDLDIHQG 631
                   ||....:........||:|..  ||...:||  |:.:|.|.:   |:.|..     .|
  Fly   537 -------YGLIGYEPLTYADYVYPSWAN--ALGWCIAGSSVVMIPAVAI---FKLLST-----PG 584

  Fly   632 SIRRNETTAST 642
            |:|:..|..:|
  Fly   585 SLRQRFTILTT 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	220/617 (36%)
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	227/644 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440732
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840