Protein Alignment CG43066 and Slc6a11

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_766478.1
• Gene: Slc6a11 / 243616
• MGIID: 95630
• Length: 627
• Species: Mus musculus
• Alignment Length: 636
• Identity: 208/636 - (32%)
• Similarity: 321/636 - (50%)
• Gaps: 113/636 - (17%)

  Fly    54 ERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQR 118
            ||..|:.|::|.||:.|..:||||:|||||||.:|||||||||::|..|..|||:|.:|..:||.
Mouse    44 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQF 108

  Fly   119 MRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLNGTGF 183
            ...|.:..|..:.|...|||.::.::...:.:||.:|:.|..|||.|.|...|||::|   |..:
Mouse   109 TSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATC---GHEW 170

  Fly   184 ELEECAK-----------------SSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVF 231
            ..|:|.:                 :|....||.|..|..:..::..|.|:|.:.|||:.:|||.:
Mouse   171 NTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICY 235

  Fly   232 FIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQ 296
            |.:.||.:|:|||||.|:.||||:|.|..|||:||.||..|:.....|.:.:|.:|.||:||.||
Mouse   236 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQ 300

  Fly   297 VFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVAS 361
            :|:|:.:..|.|.|.||||...|||.||.:::...|:.|:..|...||::|||.|
Mouse   301 IFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA---------- 355

  Fly   362 NTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVE 426
                              |||.:.:                   .:.|..|.|||||.:.:|:..
Mouse   356 ------------------YEQGVPI-------------------AEVAESGPGLAFIAYPKAVTM 383

  Fly   427 LPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDI--DIIKR-VKKQHVTGVVCLFCFIVGFI 488
            :|.:|.||.|||.||:.|||.||...:|.::..:.|:  .:.:| .:::.:...:.:..:.:|.:
Mouse   384 MPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISYFLGLV 448

  Fly   489 FCTGAGEYWLKMFDSFAGT-IGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRY 552
            ..|..|.|..::|||:|.: :.|:.||:.|.:.:.::||..||.::|..|.||||....:|.|:.
Mouse   449 MLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKV 513

  Fly   553 IGPVIMVCILVSSVVFMVIR------NPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMP 611
            :.|.|...|.    :|.:::      |..|             :||.|..||...|.|:.:|.:|
Mouse   514 VTPGICAGIF----IFFLVKYKPLKYNNVY-------------TYPAWGYGIGWLMALSSMLCIP 561

  Fly   612 I-VF---------LMRSFQCLKV---DLDIHQGSIRRNETTASTKEMIDND 649
            : :|         |....|.|.|   ||.:      |.:..||.:.:..||
Mouse   562 LWIFIKLWKTEGTLPEKLQKLTVPSADLKM------RGKLGASPRTVTVND 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	197/598 (33%)
Slc6a11	NP_766478.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		SLC6sbd_GAT3	44..585	CDD:212077	200/607 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810