Protein Alignment CG43066 and Slc6a17

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001280618.1
• Gene: Slc6a17 / 229706
• MGIID: 2442535
• Length: 727
• Species: Mus musculus
• Alignment Length: 687
• Identity: 303/687 - (44%)
• Similarity: 432/687 - (62%)
• Gaps: 63/687 - (9%)

  Fly    54 ERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQR 118
            :|.||:.|:|:.|:.||:|||||||||||||||:|||||:|:|::|:||:.|||||.:||.:|||
Mouse    59 DRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQR 123

  Fly   119 MRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPL--NGT 181
            :|.|::|||:.:.|.|||||.|||||.|||.|||||||.|..||.|.||:||||||.||:  |||
Mouse   124 IRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGT 188

  Fly   182 GFELE-ECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVV 245
            ...:| ||.|||.|||||||..||.:.|:.|.|||.|.:.|||:::|:||...|:|||||||||:
Mouse   189 VAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVM 253

  Fly   246 YFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIA 310
            ||:|||||:||..|.:||:.||||..|::||:|||::|:|:|.||.:||||||::.||.||.:||
Mouse   254 YFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIA 318

  Fly   311 FGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLG-L 374
            |.|||...|||..|..|||..|..|::.|::|:||:|||||.:..::||..|.|     |:|| |
Mouse   319 FSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAE-----KILGYL 378

  Fly   375 ND------------------TQGYEQAMSLL---NGTELLRLQLSECSLAHELDNAAEGTGLAFI 418
            |.                  |:.|.:..|::   ...:...|.|..|.|..|||.:.:|||||||
Mouse   379 NSNVLSRDLIPPHVNFSHLTTKDYSEMYSVIMTVKEKQFPALGLDPCLLEDELDKSVQGTGLAFI 443

  Fly   419 VFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTGVVCLFCF 483
            .||:|:...|.:|||:|:||.||::|||||.||.:.|:...:  ||..| |.|:..|...|:|.|
Mouse   444 AFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPI--IDTFK-VPKEMFTVGCCVFAF 505

  Fly   484 IVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQW 548
            .||.:|...:|.|::.|||.::.|:.|.|:.::|.|||.:|||.::|.:::.:|.|::|.|::.:
Mouse   506 FVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFQPYRFYFY 570

  Fly   549 TWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIV 613
            .|:::.|:.|..:..:|::.:.:..|.|.||..:........:|||.|.:.:::|....||:|:|
Mouse   571 MWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVV 635

  Fly   614 FLMRSFQCLKVDLDIHQGSIRRNETTASTKE--MIDNDDDDDEDDENDF---SGPALGGHVKTQS 673
            |::|.|..|.      .||   |..:.|.|:  |:.:..:.:|:||..|   ..|:
Mouse   636 FILRHFHLLS------DGS---NTLSVSYKKGRMMKDISNLEENDETRFILSKVPS--------- 682

  Fly   674 DFSDDDEEDKPMTMRMMMMRPTTTTKTSNVLNVPTSR 710
                  |...||......:.|.:|:...| .|.|..|
Mouse   683 ------EAPSPMPTHRSYLGPGSTSPLDN-SNNPNGR 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	280/586 (48%)
Slc6a17	NP_001280618.1	SLC6sbd_NTT4	60..648	CDD:271403	283/601 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..727		10/49 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	582	1.000	Domainoid score	I213
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H27775
Inparanoid	1	1.050	586	1.000	Inparanoid score	I995
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48419
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43410
orthoMCL	1	0.900	-	-		OOG6_101967
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870