Protein Alignment CG43066 and Slc6a20b

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_035861.2
• Gene: Slc6a20b / 22599
• MGIID: 1336891
• Length: 635
• Species: Mus musculus
• Alignment Length: 617
• Identity: 265/617 - (42%)
• Similarity: 388/617 - (62%)
• Gaps: 31/617 - (5%)

  Fly    23 ARGDGTHGVTIVLTAPQRNSVQSVDIPG-NEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQ 86
            |.|.|.|        |.|........|| .|..|..|...:||.|..|.|:|||||:||||||||
Mouse    23 AGGPGQH--------PGRPRSTECAHPGVVEKVRPKWDNPLQFLLVCISYAVGLGNVWRFPYLCQ 79

  Fly    87 QNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALY 151
            ..|||:||:|:::|||:||:||..:||.:|||||.|::|.|.||.|:|.|:||:|.:|:...::|
Mouse    80 MYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGIASLVVSFLASVY 144

  Fly   152 YNVIITWVFFYLFNSFRYPLPWSSCPLNG--TGFELEECAKSSETTYFWYRTTLDAAPSMDEPGG 214
            :|||.||..:|||:||:.|||||.||||.  ||:: |||.|:|.|.|||||.||:.:||:.|.||
Mouse   145 FNVINTWALWYLFHSFQDPLPWSVCPLNSNHTGYD-EECEKASSTQYFWYRKTLNISPSIQENGG 208

  Fly   215 LKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTP 279
            ::|...|||.|:|.:|:..:::|.:|:|||||||:..||.||.|:.:||:||.||..||.:|:||
Mouse   209 VQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTTSLPYFVLIIYLVRGLTLHGATNGLAYMFTP 273

  Fly   280 KVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIF 344
            |:|:|..|..|::||||:|:|.||..|.||||.|||.|.|:|.:..|:|||.|:.|||::|:|.|
Mouse   274 KIEQLANPKAWINAATQIFFSLGLGCGGLIAFASYNEPSNDCQKHALIVSVINSTTAIFSSIVTF 338

  Fly   345 AILGFKATVNVDRCVASNTEILVKNKLLGLND----TQGYEQAMSLLNGT------ELLRLQLSE 399
            :|.|||||.|.:.|:  |..||:......|.|    ....|:..:.|..|      |:.. .:..
Mouse   339 SIYGFKATFNYENCL--NKVILLLTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFP-HIRN 400

  Fly   400 CSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDID 464
            |||..|||.|.:||||||||:|:||..:..:..|:||:|.|||:||:||.:|....:|..|.|..
Mouse   401 CSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLTLGMGSMVGTGTAILTPLTDSK 465

  Fly   465 IIKR-VKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHE 528
            ||.. :.|:.::|:|||....:|.:|...||.||..:|:.:..|:.|:::.|:|.|||.::||.:
Mouse   466 IISSYLPKEAISGLVCLLNCAIGMVFTMEAGNYWFDLFNDYTATLSLLLIVLVETIAVCYVYGLK 530

  Fly   529 RFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVV-FMVIRNPTYGAWNADLGMIEQKSYP 592
            ||..|:..|||.....||:..|.::.|:::|.:.:..:. :::.....|.||:|..|.:..|.||
Mouse   531 RFESDLRAMTGRTLSWYWKVMWAFVSPLLIVGLFIFYLSDYILTGTLQYQAWDATQGHVVTKDYP 595

  Fly   593 NWVMGIALSMILAGVLPMPIV----FLMRSFQ 620
            .:.:.:...::.:..:.:|:|    |:.|.|:
Mouse   596 TYALAVIGLLVASSTMCIPLVALGTFVTRHFK 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	254/579 (44%)
Slc6a20b	NP_035861.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		6/22 (27%)
		SLC5-6-like_sbd	45..620	CDD:294310	254/578 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48419
OrthoDB	1	1.010	-	-		D251682at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890