Protein Alignment CG43066 and Slc6a6

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_030111163.1
• Gene: Slc6a6 / 21366
• MGIID: 98488
• Length: 631
• Species: Mus musculus
• Alignment Length: 588
• Identity: 202/588 - (34%)
• Similarity: 313/588 - (53%)
• Gaps: 81/588 - (13%)

  Fly    50 GNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELG 114
            |..|:|..||.|:.|.||:.|..|||||:|||||||.:|||||||||:.:.|...|:|:|.:|:.
Mouse    46 GKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVI 110

  Fly   115 IGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLN 179
            |||....|.:..|..|.|...|||.:|.::...:.:||.||:.|..:|||:||:..|||:.|..:
Mouse   111 IGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFHSFQKDLPWAHCNHS 175

  Fly   180 -GTGFELEECAKSSETTY--------------FWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTI 229
             .|...:|:..:.:|:.:              ||.|..|..:..:|.||.|||.:.|||:|.|.:
Mouse   176 WNTPQCMEDTLRRNESHWVSLSTANFTSPVIEFWERNVLSLSSGIDNPGSLKWDLALCLLLVWLV 240

  Fly   230 VFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAA 294
            .||.:.||::|:|||||||:.||:.:|.:..:||:||.|||.|:.....|.:.:|.:|.||:||.
Mouse   241 CFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPDISRLGDPQVWIDAG 305

  Fly   295 TQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCV 359
            ||:|:|:.:..|::.:.||||..|.|..||.:|:...|:.|:..:...||:||||.|
Mouse   306 TQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMA-------- 362

  Fly   360 ASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAI 424
                            ..||.:.|                       |.|..|.|||||.:.:|:
Mouse   363 ----------------QEQGVDIA-----------------------DVAESGPGLAFIAYPKAV 388

  Fly   425 VELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDI---DIIKRVKKQHVTGVVCLFCFIVG 486
            ..:|...||::|||.|||.|||.||...:||.:.:|.|:   .:.|..:::....::|...:::|
Mouse   389 TMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAILCSISYLLG 453

  Fly   487 FIFCTGAGEYWLKMFDSFAGT-IGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTW 550
            ....|..|.|..::||.:|.: :.|:.||..|...:.:|||.:...:.|..|.|||||.:.:::|
Mouse   454 LTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSW 518

  Fly   551 RYIGPVIMV-CILVSSVVFMVIR-NPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIV 613
            ..|.|.:.| |.:.|.|.::.:. |..|             .||:|.:|:...:.|:.:|.:|:|
Mouse   519 AVITPALCVGCFVFSLVKYVPLTYNKVY-------------RYPDWAIGLGWGLALSSMLCIPLV 570

  Fly   614 FLM 616
            .::
Mouse   571 IVI 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	200/583 (34%)
Slc6a6	XP_030111163.1	SLC5-6-like_sbd	51..592	CDD:382020	200/583 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810