Protein Alignment CG43066 and Slc6a2

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_033235.3
• Gene: Slc6a2 / 20538
• MGIID: 1270850
• Length: 617
• Species: Mus musculus
• Alignment Length: 620
• Identity: 222/620 - (35%)
• Similarity: 323/620 - (52%)
• Gaps: 104/620 - (16%)

  Fly    34 VLTAPQRNSVQ----SVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFL 94
            :|...:||.||    |.|  .:...|..|..|:.|.||::|::|.|.|:|||||||.:|||||||
Mouse    33 LLVVKERNGVQCLLASQD--SDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFL 95

  Fly    95 IPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWV 159
            ||:.:.||:.|:|||.:||.:||..|.||..||. |.|:..|:|.:..::.|:|..||||||.|.
Mouse    96 IPYTLFLIIAGMPLFYMELALGQYNREGAATVWK-ICPFFKGVGYAVILIALYVGFYYNVIIAWS 159

  Fly   160 FFYLFNSFRYPLPWSSCPLNGTGFELEECAK---------SSETTYFWYRTT------------L 203
            .:|||.||...|||::|   |..:....|..         ...|.|..|:.|            |
Mouse   160 LYYLFASFTLNLPWTNC---GHSWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHL 221

  Fly   204 DAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRG 268
            ..:..:.:.|..:|.::||||:...:::|.:.||:::|||||:.|:..||.||.:..:.|:||.|
Mouse   222 HESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPG 286

  Fly   269 AGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNA 333
            |..|:.........:|.|.|||:|||||:|:|.|..||.||||.|||...|||.||.||.|..|.
Mouse   287 ASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINC 351

  Fly   334 VTAIYASVVIFAILGFKA---TVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRL 395
            ||:..:...||:|||:.|   .||::
Mouse   352 VTSFISGFAIFSILGYMAHEHKVNIE--------------------------------------- 377

  Fly   396 QLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTL 460
                       |.|.||.||.||::.:||..|.|:.|||||||.|||:|||.|.:|.:|.::..|
Mouse   378 -----------DVATEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGL 431

  Fly   461 F-DIDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFI 524
            . |..::||.:|. .|.||.:..|::.....|..|.|.|.:.|:||....::...|||.|.|.:.
Mouse   432 ADDFQVLKRHRKL-FTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWF 495

  Fly   525 YGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVF---MVIRNPTYGAWNADLGMI 586
            ||.:||:.||.||.|::||.||:..|:::.|..::.::|.|::.   :...:.||..|
Mouse   496 YGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYTYPPW------- 553

  Fly   587 EQKSYPNWV-MGIALSMILAGVLPMPIVFLMRSFQ 620
                 .||| .|||||.::  ::|..:::...|.:
Mouse   554 -----ANWVGWGIALSSMI--LVPAYVIYKFLSIR 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	214/590 (36%)
Slc6a2	NP_033235.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SLC5-6-like_sbd	56..615	CDD:382020	215/595 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810