Protein Alignment CG43066 and dat-1

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 216/609 - (35%)
• Similarity: 313/609 - (51%)
• Gaps: 96/609 - (15%)

  Fly    40 RNSVQSVDIPGN----EPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVM 100
            :|:...:|.|.|    :|.|..||||:.|.||::|::|.|||||||||||.:||||.||||:.:|
 Worm    21 QNATLPIDGPVNTEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIM 85

  Fly   101 LILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFN 165
            ::|.|:|||.:||.:||..|.||:..|..|.|...|||....:...:|..:||||:.|...||:.
 Worm    86 VLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYT 150

  Fly   166 SFRYPLPWSSC------PL--------NGTGF-----ELEECAKSSETTYFWYRTTLDA----AP 207
            ||.:.|||:||      |.        :||..     :.....|.|....::|:..|..    ||
 Worm   151 SFSFNLPWASCNNSYNSPACYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAP 215

  Fly   208 ------SMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITL 266
                  |:.:.|.::|.|.|.|.:.:.|.:|.:.|||.:|||||:||:||||:||.|.||||:||
 Worm   216 NSHVIRSVTDLGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTL 280

  Fly   267 RGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVC 331
            .|...|:.:...|..|.|..|:||.|||||||:|.|..||.|:|:.|||...||...|.|..|..
 Worm   281 PGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFI 345

  Fly   332 NAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQ 396
            |..|:..:..|||::||:                                  ||..:|..:..:
 Worm   346 NCATSFLSGFVIFSVLGY----------------------------------MSCKSGKPIEAV- 375

  Fly   397 LSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLF 461
                        |.||.||.|:|:.:|:..:|.||||:||||.||::|||.|..|..|.::..|.
 Worm   376 ------------AQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLS 428

  Fly   462 DIDIIKRVKKQHVTGVVCLFCF--IVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFI 524
            |...|  :||.....|.|||.|  ::|...||..|...::....:..|.||::....|.:.:.:|
 Worm   429 DEFPI--LKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYI 491

  Fly   525 YGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQK 589
            ||..:|..|:.:|.|:|||.||::.|....|.|::.::.|:  |:..:..||          :..
 Worm   492 YGLRQFVHDVKEMMGFRPGNYWKFCWSCAAPFILLSMITSN--FINYQALTY----------QDY 544

  Fly   590 SYPNWVMGIALSMILAGVLPMPIV 613
            :||.....|.:...|:|...:|:|
 Worm   545 TYPTAANVIGIIFALSGASFIPLV 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	211/590 (36%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	211/590 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810