DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43066 and snf-2

DIOPT Version :9

Sequence 1:	NP_001246408.1	Gene:	CG43066 / 37129	FlyBaseID:	FBgn0262476	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	NP_492396.2	Gene:	snf-2 / 172701	WormBaseID:	WBGene00004901	Length:	746	Species:	Caenorhabditis elegans

Alignment Length:	704	Identity:	172/704 - (24%)
Similarity:	293/704 - (41%)	Gaps:	171/704 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 ERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQR 118
            :|.|:.| ::..||.:|.::|||||||||.:..||||.:|||.:::...:..:|...:|..:||.
Worm   108 DRQAFRG-IESLLSSLGQAIGLGNIWRFPTVAYQNGGTSFLIVYIICAFVFAVPAIHMEFALGQY 171

  Fly   119 MRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSF------RYPLPW---- 173
            .......|:..|.|.|.|:|..:|||...:.:||.::|:|:..|:.|.|      |...||
Worm   172 AAKSPPAVFRRIMPALEGVGWMTCIVGAVIGVYYMILISWIVLYIINIFYVNNMGRCDNPWNQNN 236

  Fly   174 -------SSC---------------------PLNGTG-----FELEECAKSSE------TTYFWY 199
                   |.|                     ||..:|     :...:|..::.      |..|:.
Worm   237 CYDGSEQSRCNKGLYSNMTANASSFLNTTMAPLMSSGSKRILYINGKCQDATNMSVEVGTEQFFS 301

  Fly   200 RTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGI 264
            ::.:..:....:...:...|:..:.|.|.|...::::|:::.||:.|.|.:.||.::....|.|:
Worm   302 KSVIRPSAGFTDFNSINLPILGAVALCWVIAAVVLIRGMKAIGKLSYVTVILPYFIIVSLLICGV 366

  Fly   265 TLRGAGAGLMHMY-TPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLV 328
            :|.||..||.|:: ......|.:...|..|..|:.:|..:..|.|:...|||....|..|||.::
Worm   367 SLPGAKDGLYHLFGQTDFNYLYKRETWTAALQQICFSLSIGQGGLMNIASYNKKTYNWYRDVYII 431

  Fly   329 SVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELL 393
            ...:.:.:|...:.:|:.|||.|                            ||:.   :|.|::
Worm   432 VFLDTLMSILGGITVFSTLGFLA----------------------------YERG---INSTDI- 464

  Fly   394 RLQLSECSLAHELDN--AAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGM 456
                       :..|  ..||..|||||:|:||.|:|....|..|||.||..||:.:::.|:| :
Worm   465 -----------DAFNHIVKEGHALAFIVYTEAIAEMPVPYLWYALFFIMLFLLGISTEVVIVE-I 517

  Fly   457 LCTLFDIDIIKRVKKQH---VTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEM 518
            :|:.. .|..:.::::.   |..|..:| |::|.:..|.||.||..|||.::..|.......:..
Worm   518 VCSCL-ADRFRYLRERRWLTVLSVSAVF-FLLGLVMTTDAGFYWFDMFDEYSTGISATFGTAIMC 580

  Fly   519 IAVIFIYGHERFTEDIFQMTG---------YRPGRY-WQWTWRYIGPVIMVCILVSSVVFMVIRN 573
            :.|.:.||...|.|||..|.|         ..|..| |...|:::.|   ||    |::.|
Worm   581 MTVFWCYGTNHFREDIAVMWGEPESWLATCLGPAAYFWTLIWKFVTP---VC----SLLMM---- 634

  Fly   574 PTYGAWNADLGMIEQKSYPN---------------WVMGIALSMILAGV------------LPMP 611
               |.|      |.:|.||:               |.:.:...:::.|.            :|:.
Worm   635 ---GLW------IWEKKYPHKGDGKIYPPVFDALGWFIAVVPFLVIPGFAIAAVINTRRMNIPIR 690

  Fly   612 IVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEMIDN---DDDDDEDDENDFSG 662
            ..|:::.         .|....|.:|.....|:.|.:   :.:..:||.|...|
Worm   691 GAFMLQK---------QHPSYDRISEQWPEWKKAIGDKLPEQEPGDDDLNMIDG 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	163/653 (25%)
snf-2	NP_492396.2	SLC6sbd	113..638	CDD:271359	153/591 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810