Protein Alignment CG43066 and mod-5

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_491095.3
• Gene: mod-5 / 171879
• WormBaseID: WBGene00003387
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 702
• Identity: 205/702 - (29%)
• Similarity: 335/702 - (47%)
• Gaps: 121/702 - (17%)

  Fly     3 ATKIIDAPRNGHEMAPLNTRARGDGTHGVTIVLTAPQRNSVQ-SVDIPGNEP------------- 53
            |..::.||.:......::.:|.....:....|...|...:|. |..|..|||
 Worm    23 AASMLSAPESRRVSRSMSVKAPTASEYMPLSVADKPLTLTVSTSHSIDPNEPIAALGGLTPTKEG 87

  Fly    54 -----------ERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIP 107
                       .|..|:.||:|.|:::||:|.||||||||.:|.::||||||||:.:||::.|:|
 Worm    88 RVAALRRRSSMVRDKWATKMEFLLAVVGYAVDLGNIWRFPSVCYKHGGGAFLIPYFIMLMIGGLP 152

  Fly   108 LFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFY----LFNSFR 168
            :|.:||.:||..|.|.:.:|..:.|...|||...|.:..|:|::||.||....::    |...:.
 Worm   153 MFYMELVLGQFHRSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQAVYFAIVSLSKIWD 217

  Fly   169 YPLPWSSCPLNGTGFELEECAKSSETT--------------YFWYRT-TLDAAPSMDEPGGLKWW 218
            ..:||:||   |..:....|:.....|              |:.|:. .:..:...|:.||:|..
 Worm   218 SEVPWASC---GNPWNTPRCSDDLNVTISRNGTPLTTPSEEYYLYKVLEVQKSTGFDDLGGVKTS 279

  Fly   219 IVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEK 283
            :.:||:..:.:|:|.:.||.|||||:|:.|:..|||:|:|..|||:.|.||..||.:..||..||
 Worm   280 MAVCLLAVFIMVYFALWKGPQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGLYYYVTPDFEK 344

  Fly   284 LLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILG 348
            |.:|.||..||||:|:|.|..||.|:|..|||...|||.||.:..|:.|..|:.::..|:|:.||
 Worm   345 LKDPAVWSAAATQIFFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFFSGCVVFSTLG 409

  Fly   349 FKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGT 413
            :.:              |:.||  .:|:..|...|
 Worm   410 YMS--------------LLTNK--PINEVVGEHDA------------------------------ 428

  Fly   414 GLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTGVV 478
            .|.|||:.||:..:..:.||:.:||.||::||:.|....:|..:....|........::....|:
 Worm   429 SLIFIVYPQALATMDYSCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDESRFLSKNRKWFVLVI 493

  Fly   479 CLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPG 543
            |:..:.:.|...:..|::.:...|.:..::.::.:...|||||.:.||.::|::||..|.|:.||
 Worm   494 CIIYYFLSFPAISYGGQFVIPFLDEYGVSLSVLFIVTCEMIAVCWFYGVDQFSKDIRAMLGFYPG 558

  Fly   544 RYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSY--PNWVMGIALSMILAG 606
            .||:..|. ..||.:      ||:|::.      .:|:....|:..||  |.|.:.:...:.|..
 Worm   559 IYWRVCWT-CSPVFI------SVIFIMT------VYNSSFKPIQMASYTFPWWSVILGWFLRLLS 610

  Fly   607 VLPMP---IVFLMRS----FQCLKVDLDIHQGSIRRNETT---ASTKEMIDN 648
            ||.:|   |::|:..    ::..:..:...|   |||..|   |...::||:
 Worm   611 VLAIPVFAIIYLLSGTGTLYERFRWAITPQQ---RRNSATSLAADPTQIIDS 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	185/585 (32%)
mod-5	NP_491095.3	SLC6sbd_SERT-like	100..639	CDD:271388	185/600 (31%)