Protein Alignment CG43066 and Slc6a9

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001342104.1
• Gene: Slc6a9 / 14664
• MGIID: 95760
• Length: 652
• Species: Mus musculus
• Alignment Length: 703
• Identity: 235/703 - (33%)
• Similarity: 360/703 - (51%)
• Gaps: 145/703 - (20%)

  Fly    33 IVLTAPQRNSVQSVDIPGNEPE------RAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGG 91
            :...:|::|..    :|....:      |..|..:::|.|:.:||:|||||:|||||||.:||||
Mouse    22 VATPSPEQNGA----VPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGG 82

  Fly    92 AFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVII 156
            ||:.|:.:|||..|||||.:||..||....|.||||. |.|...|:|....:|:.::.:||||:|
Mouse    83 AFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 146

  Fly   157 TWVFFYLFNSFRYPLPWSSC--PLNGTGFELEECA------------------------------ 189
            ...|:|.|:|..:.|||:.|  |.|     ..:||
Mouse   147 CIAFYYFFSSMTHVLPWAYCNNPWN-----TPDCAGVLDASNLTNGSRPAALSGNLSHLFNYTLQ 206

  Fly   190 KSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYI 254
            ::|.:..:|....|..:..:...|.::..::.||.:||.:||..:::|::|||||||||:.|||:
Mouse   207 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYV 271

  Fly   255 VLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKN 319
            ||||.|:||:||.||..|:|:..||:.:|:||..||.|||:|:|||.|.|:|.||...|||...|
Mouse   272 VLTILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHN 336

  Fly   320 NCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAM 384
            ||.||.:::|:.|..|::||..|||:||||.|                 |.|
Mouse   337 NCYRDSVIISITNCATSVYAGFVIFSILGFMA-----------------NHL------------- 371

  Fly   385 SLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQ 449
                |.::.|:             |..|.||||:.:.:|:..||.:|.|::|||.||:.||||:|
Mouse   372 ----GVDVSRV-------------ADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQ 419

  Fly   450 IGILEGMLCTLFDIDIIKRV-------KKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGT 507
            ..:||.::..:.|     .|       ||.:||..|.:..|::|....:.||.|||.:.|::|.:
Mouse   420 FCLLETLVTAIVD-----EVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS 479

  Fly   508 IGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIR 572
            ..|||::.:..:::::||||..:.:||..|.|:.|..::|..||::.|.|:..||:.:|:  ..|
Mouse   480 FSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVI--QYR 542

  Fly   573 NPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNE 637
            ..||..:          .||.|.:.|...|.|:.|:.:|:..|   ||..:.|.|.....: :|.
Mouse   543 PITYNHY----------QYPGWAVAIGFLMALSSVICIPLYAL---FQLCRTDGDTLLQRL-KNA 593

  Fly   638 TTASTKEMIDNDDDDDEDDENDFSGPAL-----GGHVKTQSDFSDDDEEDKPM 685
            |..|                .|: ||||     |.:..|.:...:|..|.:|:
Mouse   594 TKPS----------------RDW-GPALLEHRTGRYAPTTTPSPEDGFEVQPL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	215/600 (36%)
Slc6a9	NP_001342104.1	SLC6sbd_GlyT1	30..613	CDD:212067	230/677 (34%)