Protein Alignment CG43066 and Slc6a13

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001366036.1
• Gene: Slc6a13 / 14412
• MGIID: 95629
• Length: 602
• Species: Mus musculus
• Alignment Length: 675
• Identity: 218/675 - (32%)
• Similarity: 344/675 - (50%)
• Gaps: 118/675 - (17%)

  Fly    19 LNTRARGDGTHGVTIVLTAPQRNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPY 83
            :..||.|..::|.    |.|...:::.|:..|. .||..|:.||:|.||:.|..:||||:|||||
Mouse     1 MENRASGTTSNGE----TKPVCPAMEKVEEDGT-LEREHWNNKMEFVLSVAGEIIGLGNVWRFPY 60

  Fly    84 LCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFV 148
            ||.:||||||.||:::.|...|||:|.:|..:||....|.:..|..|.|...|||.:|.::...:
Mouse    61 LCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLL 125

  Fly   149 ALYYNVIITWVFFYLFNSFRYPLPWSSCPLNGTGFELEECAK---------------SSETTYFW 198
            .:||.|::.|..||||:||...|||.||   ...:..|.|.:               :|....||
Mouse   126 NVYYIVVLAWALFYLFSSFTTDLPWGSC---SHEWNTENCVEFQKANDSMNVTSENATSPVIEFW 187

  Fly   199 YRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRG 263
            .|..|..:..:...|.|:|.:||||:|:|.|.:|.:.||::|:|||||||:.|||::|.:..|||
Mouse   188 ERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRG 252

  Fly   264 ITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLV 328
            :||.||..|:.....|.:.:|.:|.||:||.||:|:||.:..|.|.|.||||...|||.||.:.:
Mouse   253 VTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIAL 317

  Fly   329 SVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELL 393
            .:.|:.|:..|...||:||||                        ::..||
Mouse   318 CILNSSTSFMAGFAIFSILGF------------------------MSQEQG-------------- 344

  Fly   394 RLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLC 458
             :.:||.        |..|.|||||.:.:|:|.||.:|.||..||.|::.|||.||...:|.::.
Mouse   345 -VPISEV--------AESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVT 400

  Fly   459 TLFDIDIIKRV-----KKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGT-IGLVVVALME 517
            .|  :|:..||     :::.:..:|.:..|.:|.|..|..|.|..::||.:|.: :.|:.||:.|
Mouse   401 AL--VDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFE 463

  Fly   518 MIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIR-NP------- 574
            .:.|.::||..||.::|..|.||:|....::.|.:..|.  ||:  ::.:|.:|: .|
Mouse   464 SLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPA--VCL--ATFLFSLIKYTPLTYNKKY 524

  Fly   575 TYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNETT 639
            ||..|...||         |::.:: |||   .:|...::.:|:.          :|.:|..
Mouse   525 TYPWWGDALG---------WLLALS-SMI---CIPAWSIYKLRTL----------KGPLRER--- 563

  Fly   640 ASTKEMIDNDDDDDEDDENDFSGPA 664
              .::::...:|..:.::.:.:.||
Mouse   564 --LRQLVCPAEDLPQKNQPEPTAPA 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	203/590 (34%)
Slc6a13	NP_001366036.1	SLC5-6-like_sbd	32..575	CDD:382020	207/626 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810