Protein Alignment CG43066 and ine

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_061510082.1
• Gene: ine / 1279910
• VectorBaseID: AGAMI1_010349
• Length: 885
• Species: Anopheles gambiae
• Alignment Length: 716
• Identity: 210/716 - (29%)
• Similarity: 343/716 - (47%)
• Gaps: 125/716 - (17%)

  Fly    47 DIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLI 111
            |:...:|.:..|:.||||.|:.|||||||||:|||||||.::|||.||:|:.::|::.|||:..:
Mosquito   242 DLDNLKPRKQHWANKMQFVLACIGYSVGLGNVWRFPYLCYKSGGGVFLVPYFIILLICGIPMLFM 306

  Fly   112 ELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC 176
            ||.:||....|.:|....:.|...|.|::|.:|:..::.||:|||.:..:|.|.|||..|||:.|
Mosquito   307 ELAVGQYTGRGPIGALGQLCPLFKGTGLASVVVSFLMSTYYSVIIAYAIYYFFTSFRPELPWTDC 371

  Fly   177 PLNGTGFELEEC--------------AKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSW 227
               ...:...:|              ...:.|..|:....|..:..::.||.::|.:|.||:.:|
Mosquito   372 ---SHRWNTPDCWIPERLKHNLTRPDMSRTPTEEFFENKVLQISHGIEYPGAMRWELVACLVCAW 433

  Fly   228 TIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLD 292
            .:|:|.:.|.|:||.||.|.|:..|::::.:|..|.:||.||..||.:.:.|..|:|....||::
Mosquito   434 ILVYFAIWKSIKSSAKVRYLTATLPFVLIVVFLGRSLTLEGADKGLHYFFRPNWEELGRANVWIN 498

  Fly   293 AATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDR 357
            ||.|.|.|.|:||||:|:|.|||...||.:.|.|.||..||:|::...:..||.:|     |:
Mosquito   499 AAAQNFNSIGIAFGSMISFASYNKYNNNILHDTLAVSFVNAITSLLVGIFAFATIG-----NI-- 556

  Fly   358 CVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQ 422
            .:..||  .|:|.:.|                                      |.||.|:|:.|
Mosquito   557 ALEQNT--TVENVISG--------------------------------------GPGLIFVVYPQ 581

  Fly   423 AIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFD--IDIIKRVKKQH--VTGVVCLFCF 483
            |:.::|.|..||||||.|||.|||.||..|:|.::.::.|  ...|||....|  :..:||:..|
Mosquito   582 ALAKMPAAQLWAVLFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRKLVYHELLVLIVCVVSF 646

  Fly   484 IVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQW 548
            ..|.......|.|:.::.|.:|.::.::.:|..|.||:.:.||..|.::::.||||..|..|.::
Mosquito   647 FAGLPNLIQGGIYFFQLIDHYAASVSIMFLAFFETIAIAWFYGINRLSKNVKQMTGRYPSFYLRF 711

  Fly   549 TWRYIGPVIMVCILVSSVVFMVIRNPTY--GAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMP 611
            ......|::::.:.:.|::  ....|||  |.::          ||.|..|:..::..|.::.:|
Mosquito   712 CLLIAVPLLLISLWIFSLI--NYEAPTYHNGKYH----------YPGWAHGLGWTIASASLVCIP 764

  Fly   612 IVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEM-----------IDNDDDDDEDDENDFSGPAL 665
                  |:...::        :|....|...|.:           |..:...|.|..::..||.:
Mosquito   765 ------SYAVYQI--------VRAEGNTFGEKLLNTLKPNIYECKICGEHHCDHDFPDEELGPEM 815

  Fly   666 -----------------GGHVK-TQSDFSDDDEEDKPMTMRMMMMRPTTTTKTSNVLNVPTSRKN 712
                             .||:: ||.......::....:....|:|.|.|.......|.|.:..:
Mosquito   816 TIVESTSGAPLILQPPPPGHLQYTQLQQQQQHQQQHQQSQDEPMLRTTNTNSPPPTTNGPQNSNS 880

  Fly   713 N 713
            |
Mosquito   881 N 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	188/581 (32%)
ine	XP_061510082.1	None