Protein Alignment CG43066 and Slc6a15

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001239259.1
• Gene: Slc6a15 / 103098
• MGIID: 2143484
• Length: 729
• Species: Mus musculus
• Alignment Length: 669
• Identity: 278/669 - (41%)
• Similarity: 428/669 - (63%)
• Gaps: 45/669 - (6%)

  Fly    33 IVLTAPQRNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPF 97
            :::...:.....:.|....:.||.||:.|:|:.|:.:|:||||||:||||||||:|||||:|:|:
Mouse    39 LIVDVQEEKDTDAEDGSEADDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPY 103

  Fly    98 MVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFY 162
            :::|::.|||||.:||.:|||:|.|::||||.|.|.|||||.:||:|..||||||||||.|..||
Mouse   104 LILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFY 168

  Fly   163 LFNSFRYPLPWSSCPL--NGTGFELE-ECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLM 224
            ...||:.||||..|||  |.:...:| ||.:||.|||:|||..||...|:.:.|||.|.:.:||:
Mouse   169 FSQSFQQPLPWDQCPLVKNASHTYVEPECEQSSATTYYWYREALDITSSISDSGGLNWKMTVCLL 233

  Fly   225 LSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTV 289
            ::|.:|...::||||||||::||:|||||:||..|.||.:.|.|:..|:.||:|||:|.:|||.|
Mouse   234 VAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEMMLEPKV 298

  Fly   290 WLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVN 354
            |.:||||||::.||.||.:|||.|||...|||..|.:|||..|..|::.|::|:||:|||||.:.
Mouse   299 WREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIV 363

  Fly   355 VDRCVASNTEILVKNKLLG-----------------LNDTQGYEQAMSLLNGTELLRLQLSECSL 402
            .::|::.|:|:::|...:|                 :.|.:.....:..:...|...|.|:.|.:
Mouse   364 NEKCISQNSEMILKLLKMGNISWDVIPHHINLSAVTVEDYRLVYDIIQKVKEEEFAVLHLNACQI 428

  Fly   403 AHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIK 467
            ..||:.|.:|||||||.||:|:...|.:|||:|:||.||::|||||..|.:||::..:  :|..|
Mouse   429 EDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPI--VDTFK 491

  Fly   468 RVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTE 532
             |:|:.:|.:.||..|.:|.||...:|.|::.|||.::.|:.|::|.::|.|||.|:||.::|.|
Mouse   492 -VRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYGIDKFIE 555

  Fly   533 DIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMG 597
            |:..|.|:.|.:|:.:.|:||.|::::.:|::|:|.|.:..|.|.||..:....|..|||.|.|.
Mouse   556 DLTDMLGFAPSKYYYYMWKYISPLMLLTLLIASIVNMGLSPPGYNAWIKEKASEEFLSYPMWGMV 620

  Fly   598 IALSMILAGVLPMPIVFLMRSFQCLKVD--------LDIHQGSIRRNETTASTKEMIDNDDDDDE 654
            :..|:::..:||:|:||::|  :|..:|        :...:|.:        .||.::.:.||..
Mouse   621 VCFSLMVLAILPVPVVFIIR--RCNLIDDSSGNLASVTYKRGRV--------LKEPVNLEGDDAS 675

  Fly   655 ----DDENDFSGPALGGHV 669
                ...::.|.|..|.::
Mouse   676 LIHGKIPSEMSSPNFGKNI 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	265/581 (46%)
Slc6a15	NP_001239259.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..61		1/18 (6%)
		SLC6sbd_SBAT1	61..640	CDD:212091	265/581 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	582	1.000	Domainoid score	I213
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	586	1.000	Inparanoid score	I995
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48419
OrthoDB	1	1.010	-	-		D251682at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43410
orthoMCL	1	0.900	-	-		OOG6_101967
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4904
SonicParanoid	1	1.000	-	-		X1148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910