Protein Alignment CG43066 and Slc6a8

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_598748.1
• Gene: Slc6a8 / 102857
• MGIID: 2147834
• Length: 640
• Species: Mus musculus
• Alignment Length: 639
• Identity: 213/639 - (33%)
• Similarity: 328/639 - (51%)
• Gaps: 116/639 - (18%)

  Fly    12 NGHEMAPLNTRARGDGTHGVTIVLTAPQRNSVQSVDIPGNE---PERAAWSGKMQFFLSIIGYSV 73
            :|.:.||    |:|||..|               :..||..   |.|..|:.:|.|.:|.:|::|
Mouse    25 SGPDGAP----AKGDGPAG---------------LGAPGGRLAVPPRETWTRQMDFIMSCVGFAV 70

  Fly    74 GLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIG 138
            ||||:|||||||.:||||.||||::::.::.|||:|.:|:.:||.|:.|::.||| |.|...|:|
Mouse    71 GLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWN-ICPLFKGLG 134

  Fly   139 ISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC------PLNGTGFELEECA-------- 189
            .:|.::..:...||.:::.|.|:||..||...|||::|      |.....|..|:||
Mouse   135 YASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLT 199

  Fly   190 ------KSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFT 248
                  :.|....||....|..:..::.||.|.|.:.|||:..|.:|:|.|.||::|:||:||||
Mouse   200 CDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFT 264

  Fly   249 SLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGS 313
            :.|||:||.:..:||:.|.||..|:::...|...||..|.||:||.||:|:|:.:..|:|.|.||
Mouse   265 ATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGS 329

  Fly   314 YNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQ 378
            ||...|||.:|.:::::.|:.|:.:|..|:|:||||.||
Mouse   330 YNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAT-------------------------- 368

  Fly   379 GYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLS 443
              ||.:                   |....|..|.|||||.:.:|:..:|.||.||.|||.|||.
Mouse   369 --EQGV-------------------HISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLL 412

  Fly   444 LGLGSQIGILEGMLCTLFDI---DIIKRVKKQHVTGVVCLFCFIVGFIFCTG-----AGEYWLKM 500
            |||.||...:||.:..|.|:   ....|.:::....:.|..||::.....|.     .|.|..::
Mouse   413 LGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDVSGGKGGMYVFQL 477

  Fly   501 FD--SFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILV 563
            ||  |.:||. |:..|..|.:.|.::||.:||.:||..|.||||..:.:|.|.:..|::.:.|.:
Mouse   478 FDYYSASGTT-LLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFI 541

  Fly   564 SSVVFM--VIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFL 615
            .::|:.  ::.|.||             .||.|...:..:..|:.:|.:|:..|
Mouse   542 FNIVYYEPLVYNNTY-------------VYPWWGEAMGWAFALSSMLCVPLHLL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	202/593 (34%)
Slc6a8	NP_598748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		0/1 (0%)
		SLC6sbd_CT1	52..626	CDD:271397	202/593 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810