Protein Alignment CG43066 and slc6a16

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_004916326.1
• Gene: slc6a16 / 100497867
• XenbaseID: XB-GENE-996340
• Length: 677
• Species: Xenopus tropicalis
• Alignment Length: 669
• Identity: 288/669 - (43%)
• Similarity: 406/669 - (60%)
• Gaps: 50/669 - (7%)

  Fly    48 IPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIE 112
            :|.....|..|..|:|:.|:.:|:||||||:|||||||.|||||:||:.:.::|::.|||||.:|
 Frog    21 LPAESVARPTWGSKVQYILAQVGFSVGLGNVWRFPYLCHQNGGGSFLLLYFLLLLIIGIPLFFLE 85

  Fly   113 LGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCP 177
            |..||.:|.|::|||..|.|.|.|||.:||:|..||||||||||.|..|||||||.|||||.:||
 Frog    86 LAAGQSIRQGSIGVWKHISPRLAGIGFASCVVCGFVALYYNVIIGWSLFYLFNSFHYPLPWENCP 150

  Fly   178 -LNGTGFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSS 241
             |.....|:.||||||.|||||||:.|:...:: |...:.|.:..||.|:|.:|...::|||:||
 Frog   151 TLPNMTQEVTECAKSSNTTYFWYRSALNVTNTI-ESSEMNWPMTGCLCLAWFLVCGGMIKGIKSS 214

  Fly   242 GKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFG 306
            |||:||:|:|||:||..|.|||:.|.||..|:..|:|||:|......||..||||||::.||.||
 Frog   215 GKVMYFSSVFPYVVLFCFLIRGLLLEGAADGIRIMFTPKLEIWGNIQVWRQAATQVFFALGLGFG 279

  Fly   307 SLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTE---ILVK 368
            |:||:.|||..:|||..|.:|||..|.:|:|.|::|:||:|||:|......|:.:|.|   .|:.
 Frog   280 SVIAYSSYNDRQNNCHFDAILVSFINFMTSILATLVVFAVLGFRANDLTRHCIDTNREKILYLIS 344

  Fly   369 NKLL--------GLNDTQGYEQAMSLLNGTELLRLQ---LSECSLAHELDNAAEGTGLAFIVFTQ 422
            |..|        .|.::: |.|...:.|.|  |.||   :|:|.:...::...||||||||.||:
 Frog   345 NGSLYENIVPMKNLTNSE-YSQWYEITNNT--LNLQQYGISDCRVEDVMNEGVEGTGLAFIAFTE 406

  Fly   423 AIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTGVVCLFCFIVGF 487
            |:...|.:|||::|||.|||:|||.:..|.::|::..|.|.....|.||...|.:.|:...::|.
 Frog   407 AMTRFPASPFWSILFFLMLLNLGLSTMFGNMQGIITPLLDNFPYLRKKKTIFTVICCITGLLIGL 471

  Fly   488 IFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRY 552
            ||...:|.|::.|||.::.|:.|::|.:.|.|||.::||.|||.:||..|.|:||.|.:::.|:|
 Frog   472 IFVQRSGSYFVSMFDDYSATLPLIIVVIFENIAVAWVYGAERFMDDIGGMLGHRPWRIYKYIWQY 536

  Fly   553 IGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPIVFLMR 617
            |..:.|:.:|::|::.|.|..|.|.|||.:....|...||.|.:|:..|:|:...||:|||||..
 Frog   537 ISILGMIGLLLASLIRMCIEYPRYQAWNQEQAKKEMLEYPPWALGMLTSLIIVAALPIPIVFLKH 601

  Fly   618 SFQ--CLK------VDLDIHQGSIRRNETTASTKEMIDNDDDDDED-----------DENDFSGP 663
            ..|  .||      .|.|..||:        :..:||....:...|           :..||
 Frog   602 IIQDWILKWKTKTYGDCDYTQGN--------TVDDMIGPIVESPADLGYVGNGYLPVEMEDF--- 655

  Fly   664 ALGGHVKTQSDFSDDDEED 682
            |..|.:.|:.|. ||.|||
 Frog   656 AERGKLTTEEDL-DDAEED 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	266/576 (46%)
slc6a16	XP_004916326.1	SLC5-6-like_sbd	28..599	CDD:382020	264/574 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	582	1.000	Domainoid score	I212
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	589	1.000	Inparanoid score	I978
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D251682at33208
OrthoFinder	1	1.000	-	-		FOG0001784
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060