Protein Alignment CG43066 and slc6a6

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 624
• Identity: 211/624 - (33%)
• Similarity: 327/624 - (52%)
• Gaps: 102/624 - (16%)

  Fly    50 GNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELG 114
            |..|:|..|:.|:.|.||:.|..:||||:|||||||.:|||||||||:.:.|...|:|:|.:|:.
 Frog    36 GKPPQREKWASKIDFVLSVAGGFIGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVV 100

  Fly   115 IGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC--- 176
            :||....|.:..|..|.|...|||.:|.::...:.:||.||:.|..:|||.||:..|||:.|
 Frog   101 LGQFTSEGGITCWEKICPVFTGIGYASIVIVSLLNVYYIVILAWGVYYLFQSFQGQLPWALCHQP 165

  Fly   177 -------------------PLNGTGFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLC 222
                               .:|.|.|       :|..|.||....|..:..:|:.|.|||.:.||
 Frog   166 WNTESCVEDTFRKNWTMWMSMNSTNF-------TSPVTEFWEHKVLSLSKGIDDVGVLKWDLALC 223

  Fly   223 LMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEP 287
            |:|:|.|.||.:.||::|:|||||||:.||:|:|.:..|||:||.||..|:.....|.:.:|.:|
 Frog   224 LLLTWVICFFCIWKGVRSTGKVVYFTATFPFIMLLVLLIRGVTLPGAAEGIKFYLYPDITRLADP 288

  Fly   288 TVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKAT 352
            .||:||.||:|:|:.:..|::.:.||||..|.||.||.:|:...|:.|:..:...||::|||.|
 Frog   289 QVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGFAIFSVLGFMA- 352

  Fly   353 VNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAF 417
                                   ..||.:.|                       |.|..|.||||
 Frog   353 -----------------------QEQGVDIA-----------------------DVAESGPGLAF 371

  Fly   418 IVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDI---DIIKRVKKQHVTGVVC 479
            |.:.:|:..:|...|||:|||.|||.|||.||...:||.:.:|.|:   .:.|..:::....|||
 Frog   372 IAYPKAVSMMPLPSFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAVVC 436

  Fly   480 LFCFIVGFIFCTGAGEYWLKMFDSFAGT-IGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPG 543
            ...:::|....|..|.|..::||.:|.: :.|:.||..|.:||.::||.::|.::|..|.||:||
 Frog   437 FLSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECVAVAWVYGADKFYDNIEDMIGYKPG 501

  Fly   544 RYWQWTWRYIGPVIMV-CILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGV 607
            .:.:|:|..|.|::.| |.:.|...:..:   ||..:..         ||:|.:|:...:.|:.:
 Frog   502 PWMKWSWTVITPLLCVACFIFSLAKYTPL---TYNKYYV---------YPDWAIGLGWVLALSSM 554

  Fly   608 LPMPIVFLMRSFQCLKVDLDIHQGS-IRRNETTASTKEM 645
            :.:|:|.:   |..::.|     || |.|.:...:.:|:
 Frog   555 ICIPLVVV---FHIVRSD-----GSLIERIKAVTAPREV 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	202/588 (34%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	208/614 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910