Protein Alignment CG43066 and slc6a9

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_004914027.1
• Gene: slc6a9 / 100492204
• XenbaseID: XB-GENE-948182
• Length: 638
• Species: Xenopus tropicalis
• Alignment Length: 685
• Identity: 232/685 - (33%)
• Similarity: 353/685 - (51%)
• Gaps: 134/685 - (19%)

  Fly    48 IPG------NEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGI 106
            :||      ..|:|..|..:::|.|:.:||:|||||:|||||||.:||||||:.|:.:||:..||
 Frog    14 VPGEATKKDENPKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGI 78

  Fly   107 PLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPL 171
            |||.:||..||....|.||||. :.|...|:|....:|:.::.:||||:|...|:|.|.|....|
 Frog    79 PLFFMELSFGQFASQGCLGVWR-VSPIFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFASMNRIL 142

  Fly   172 PWSSCPLNGTGFELEECA-------------------------------KSSETTYFWYRTTLDA 205
            ||:.|   ...:..|.||                               ::|.:..:|.|..|:.
 Frog   143 PWTYC---NNLWNTENCAGVLSPNSSATFNISSQHSLLNLTMGLNQTLKRTSPSEEYWRRHVLNI 204

  Fly   206 APSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAG 270
            :..:.:.|.::..::.||.:||.:||..:::|::|||||||||:.|||:||||.|||||||.||.
 Frog   205 SGDIGDFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFIRGITLDGAI 269

  Fly   271 AGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVT 335
            .|:::..||:.:|:|...||.|||:|:|||.|.|:|.||...|||...|||.||.:::|:.|..|
 Frog   270 NGILYYLTPQWDKILHAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSIIISITNCAT 334

  Fly   336 AIYASVVIFAILGFKAT-VNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSE 399
            ::||..|||:||||.|| :.||                                        :||
 Frog   335 SVYAGFVIFSILGFMATHLGVD----------------------------------------VSE 359

  Fly   400 CSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFD-- 462
            .        |..|.||||:.:.:|:..||.:|.|::|||.||:.||||:|..:||.::..:.|
 Frog   360 V--------ADHGPGLAFVAYPEALTLLPISPLWSILFFFMLILLGLGTQFCLLETLVTAIVDEI 416

  Fly   463 -IDIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYG 526
             .|.|.|.|.. ||..|.:..|::|....|.||.|||.:.|::|.:..||:::.:..|||::|||
 Frog   417 GSDWIIRWKTL-VTLGVAIIGFLLGIPLTTQAGIYWLLLMDNYAASFSLVIISCIMCIAVMYIYG 480

  Fly   527 HERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVV-FMVIRNPTYGAWNADLGMIEQKS 590
            |..:.:||..|.|:.|..::|:.||:..|.|:..||:.:|: :..|:...|             .
 Frog   481 HRNYFKDIEMMLGFPPPLFFQFCWRFFSPAIIFFILIFTVIQYRPIKYNDY-------------V 532

  Fly   591 YPNWVMGIALSMILAGVLPMPIVFLMRSFQCLKVDLDIHQGSIRRNETTASTKEMIDNDDDDDED 655
            ||:|.:.|...|.|:.|:.:|:..:.|.::.     :.|....|.......:|:.
 Frog   533 YPDWALTIGFLMALSSVICIPLYAVFRVWRS-----EGHTFLQRLKNAVKPSKDW---------- 582

  Fly   656 DENDFSGPAL-----GGHVKTQSDFSDDDEEDKPM 685
                  ||||     |.:.:..|...|.:.|.:|:
 Frog   583 ------GPALLEHRTGRYAQISSSRCDSNPEAQPL 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	216/597 (36%)
slc6a9	XP_004914027.1	SLC6sbd_GlyT1	11..595	CDD:212067	228/667 (34%)