Protein Alignment CG43066 and slc6a12

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_031754510.1
• Gene: slc6a12 / 100492029
• XenbaseID: XB-GENE-6033368
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 630
• Identity: 213/630 - (33%)
• Similarity: 323/630 - (51%)
• Gaps: 106/630 - (16%)

  Fly     5 KIIDAPRNGHEMAPLNTRARGDGTHGVTIVLTAPQRNSVQSVDIPGNEPE---RAAWSGKMQFFL 66
            |..:.||||...:. ...|.|:|.|                     .|||   |..||.|::|.|
 Frog     4 KDCEKPRNGAGGSD-TLCALGEGRH---------------------REPEIEDRGQWSNKVEFVL 46

  Fly    67 SIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIH 131
            |:.|..:||||:|||||||.:||||||.||:::.|...|||:|.:|..:||....|.:..|..|.
 Frog    47 SVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTSQGGITAWRKIC 111

  Fly   132 PWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPLNGTGFELEECA------- 189
            |...|||.:|.::..::.:||.||:.|..||||:||...|||::|  |.| :..|.|.
 Frog   112 PLFEGIGYASQVIEGYLNIYYIVILAWALFYLFSSFTAELPWATC--NNT-WNTEHCIDFVGKSE 173

  Fly   190 -------KSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYF 247
                   .:|....||.|..|..:..::..|.::|.:.|||:|:|.|.:|.:.||::|:||||||
 Frog   174 NFTSLENSTSSVVEFWERRVLHLSEGIEHLGNVRWDLALCLLLAWIICYFCIWKGVKSTGKVVYF 238

  Fly   248 TSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFG 312
            |:.|||::|.|..:||:||.||..|::....|.:.:|.:|.||:||.||:|:|:.:..|.|.|.|
 Frog   239 TATFPYVMLIILLVRGVTLPGAYEGIIFYLKPDMTRLQDPQVWMDAGTQIFFSYAICQGCLTALG 303

  Fly   313 SYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDT 377
            |||...|||.||.:.:...|::|:..|...||::|||.|                        ..
 Frog   304 SYNKYNNNCYRDCIALCFLNSITSFVAGFAIFSVLGFMA------------------------QE 344

  Fly   378 QGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLL 442
            ||               :.:||.        |..|.|||||.:.:|:..:|.:|.|:.|||.||:
 Frog   345 QG---------------VPISEV--------AESGPGLAFIAYPKAVTMMPVSPLWSCLFFLMLI 386

  Fly   443 SLGLGSQIGILEGMLCTLFDI---DIIKRVKKQHVTGVVCLFCFIVGFIFCTGAGEYWLKMFDSF 504
            .|||.||...:|.::..:.|:   ...|:.:::.....|.:.|:::|.|..|..|.|..::||.:
 Frog   387 FLGLDSQFVCVESLVTAIVDMFPHVFRKKYRREFFILAVAVICYLLGLILLTEGGMYVFQLFDYY 451

  Fly   505 A--GTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVV 567
            |  ||. |:.||:.|:|.|.::||..||.::|..|.||||....::.|.:..|.  ||:  .:.:
 Frog   452 AASGTC-LLFVAIFEVICVGYVYGANRFYDNIEDMIGYRPWPLVKYCWLFATPA--VCL--GTFL 511

  Fly   568 FMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPMPI 612
            |.:|:       .:.|....:..||:|...|...|.|:.::.:||
 Frog   512 FSLIK-------YSPLKYNNRYVYPSWGYAIGWLMALSSMICIPI 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	201/577 (35%)
slc6a12	XP_031754510.1	SLC5-6-like_sbd	34..572	CDD:382020	201/578 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000