Protein Alignment CG43066 and slc6a15

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 655
• Identity: 282/655 - (43%)
• Similarity: 426/655 - (65%)
• Gaps: 35/655 - (5%)

  Fly    40 RNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILE 104
            |:..:..||   :.||.||:.|:|:.|:.:|:||||||:||||||||:|||||:|:|::::|:|.
 Frog    49 RDIEEGSDI---DDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLI 110

  Fly   105 GIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRY 169
            |||:|.:||.:|||:|.|::||||.|.|.:||||.:||||.|||||||||||.|..||...||::
 Frog   111 GIPVFFLELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQSFQH 175

  Fly   170 PLPWSSCPL--NGTGFELE-ECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVF 231
            ||||..|||  |.:...:| ||.|||.|||:|||..|:.:.|:.|.|||.|.:.|||:.:|.:|.
 Frog   176 PLPWDQCPLVKNASNTFVEPECEKSSATTYYWYREALNISNSITEGGGLNWKMTLCLLAAWILVC 240

  Fly   232 FIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQ 296
            ..::|||||||||:||:|||||:|||.|.:|.:.|.|:..|:.||:|||:|.:|||.||.:||||
 Frog   241 LAMIKGIQSSGKVMYFSSLFPYVVLTCFLVRALLLNGSVDGIRHMFTPKLEIMLEPKVWREAATQ 305

  Fly   297 VFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCVAS 361
            ||::.||.||.:|||.|||...|||..|.:|||..|..|::.|::|:||:|||||.:..:.|::.
 Frog   306 VFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNENCISK 370

  Fly   362 NTEILVKNKLLG----------LNDTQGYEQAMSL-------LNGTELLRLQLSECSLAHELDNA 409
            ||..:||....|          :|.:....|..:|       :...|...|.|..|.:..||:.:
 Frog   371 NTVKIVKYLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQKIKEEEFDSLGLDSCQIEDELNKS 435

  Fly   410 AEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHV 474
            .:|||||||.||:|:...|.:|||:|:||.||::|||||..|.:||::..:  :|..| |:|:.:
 Frog   436 VQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIITPI--VDTFK-VRKEPL 497

  Fly   475 TGVVCLFCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTG 539
            |...||..|.:|.:|...:|.|::.|||.::.|:.|::|.::|.:|:.::||.::|.:|:..|.|
 Frog   498 TVGCCLLAFCIGLLFVQRSGNYFVTMFDDYSATLPLLIVVILENVAIAWVYGIDKFMDDLKDMLG 562

  Fly   540 YRPGRYWQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMIL 604
            :.|.:|:.:.|:||.||::..:|::|:|.|....|.|.||.|:....|:.|||.|.:.:.:|:|:
 Frog   563 FTPYKYYYYMWKYISPVLLTILLMASIVQMGFSPPGYYAWIAEKASEERISYPPWGLAVCISLIV 627

  Fly   605 AGVLPMPIVFLMRSFQCLKVDLDIHQGSI-----RRNETTASTKEMIDNDDDDDEDDENDFSGPA 664
            ..:||:|:||::|:...    :|...||:     :|.:....|..:.|:.....|..:::...|.
 Frog   628 FALLPVPVVFIVRTCNL----IDDSTGSLASVSYKRGKMIKETSNLEDDASLIHEKIQSEMPSPN 688

  Fly   665 LGGHV 669
            :|..:
 Frog   689 IGSSI 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	268/581 (46%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:444915	268/581 (46%)