DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43066 and si:ch211-117c9.5

DIOPT Version :9

Sequence 1:	NP_001246408.1	Gene:	CG43066 / 37129	FlyBaseID:	FBgn0262476	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	XP_001922963.4	Gene:	si:ch211-117c9.5 / 100150452	ZFINID:	ZDB-GENE-110408-2	Length:	652	Species:	Danio rerio

Alignment Length:	604	Identity:	206/604 - (34%)
Similarity:	317/604 - (52%)	Gaps:	98/604 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 ERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQR 118
            :|..||.:|.|.:|.:|::|||||:|||||||.:||||.||||:::|:...|||:|.:|:.:||.
Zfish    62 DRQTWSRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILMVFFGGIPVFFLEIALGQF 126

  Fly   119 MRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSC------- 176
            |:.|.:..|| |.|...|:|::|.::..|...||.:::.|..::|.:||...|||::|
Zfish   127 MKQGGVATWN-IAPLFKGLGLASMVIVFFCNTYYIMVLVWGLYFLAHSFTSSLPWATCGHEWNTI 190

  Fly   177 ---------------------PLNGTGFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIV 220
                                 .||.:...||.....|....||.|..|..:..:||.|.:...:|
Zfish   191 NCTTNFSRVCFNQSPSHPNNSSLNISAGCLEPTGLRSSVMEFWERKVLRLSGGLDEVGDISGHMV 255

  Fly   221 LCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLL 285
            |||:.:|.||:|.:.||::|:|||||||::|||:||.:.|:.|::|.||..|:::...|...||.
Zfish   256 LCLLATWIIVYFCIWKGVKSAGKVVYFTAVFPYLVLVVLFVHGVSLPGAINGIIYYLKPNWSKLS 320

  Fly   286 EPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFK 350
            |..||:|||||:|:|:.:..|:|.|.||||...|||.:|..::::.|:.|:.:|..|:|::|||.
Zfish   321 EAQVWIDAATQIFFSYAIGLGALTALGSYNRFNNNCYQDAFILALINSGTSFFAGFVVFSVLGFM 385

  Fly   351 ATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAE-GTG 414
            |.                            ||.:                    ::.|.|| |.|
Zfish   386 AA----------------------------EQDV--------------------DISNVAESGPG 402

  Fly   415 LAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDI----DIIKRVKKQHVT 475
            ||||.:.:|:..:|.||.||||||.|||.|||.||...:||.:..:.|:    ..|..::::.|.
Zfish   403 LAFIAYPKAVSLMPLAPLWAVLFFLMLLVLGLDSQFVGVEGFITGIMDMLPPKSFIGSLRREVVV 467

  Fly   476 GVVCLFCFIVGFIFCTGAGEYWLKMFDSF-AGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTG 539
            .:.|..||.:.....|..|.|..::||.: |..|.|:..|..|.:.|.::||.:||.:|:..|.|
Zfish   468 AICCFTCFTIDLSMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVVAWVYGADRFMDDVACMIG 532

  Fly   540 YRPGRYWQWTWRYIGPVIMVCILVSSVV--FMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSM 602
            |||..|.:|.|.||.||:.:.:.:..||  ..::.|..|             .||.|...:...:
Zfish   533 YRPLPYMKWCWSYITPVVCMGVFLFHVVNYKRLVYNAVY-------------VYPWWGEALGWFL 584

  Fly   603 ILAGVLPMPIVFLMRSFQC 621
            .|:.:|.:|:..|.:...|
Zfish   585 ALSSMLCIPLTVLYKLLHC 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	205/597 (34%)
si:ch211-117c9.5	XP_001922963.4	SLC5-6-like_sbd	63..652	CDD:294310	206/603 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810