Protein Alignment CG43066 and slc6a18

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001108369.2
• Gene: slc6a18 / 100141332
• ZFINID: ZDB-GENE-080219-9
• Length: 618
• Species: Danio rerio
• Alignment Length: 595
• Identity: 283/595 - (47%)
• Similarity: 399/595 - (67%)
• Gaps: 25/595 - (4%)

  Fly    36 TAPQRNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVM 100
            ||.:.:|||         ||..|..|:|:.|:.:|::||||||||||||||..||||||||:::.
Zfish     3 TASETSSVQ---------ERPKWDNKVQYLLTCVGFAVGLGNIWRFPYLCQIYGGGAFLIPYLIA 58

  Fly   101 LILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFN 165
            |:.||:||..:||.|||.:|.|::|||::|.|.|||:|::|.:|:..|.|:||.|:.||.:|.|:
Zfish    59 LVFEGLPLLYLELAIGQSLRKGSIGVWHSISPLLGGVGVASMVVSFLVGLFYNTILAWVLWYFFH 123

  Fly   166 SFRYPLPWSSCPLNGT--GFELEECAKSSETTYFWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWT 228
            ||..|||||.||:|..  |: :|||..|:...|:|||.||:.:|.:::.|.|:|.:||||..:|:
Zfish   124 SFEDPLPWSQCPINDNLEGY-VEECVSSTPVNYYWYRQTLNISPDIEQSGSLQWTLVLCLATAWS 187

  Fly   229 IVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWLDA 293
            ||:...::||::.||.||.|:.|||:|||||.:|.:||.||..||.:::||....|..|.|||||
Zfish   188 IVYICFIRGIETIGKAVYVTATFPYLVLTIFLVRALTLPGATDGLQYLFTPDWSLLTNPQVWLDA 252

  Fly   294 ATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRC 358
            |||:|:|..||||.||||.|||..||:|.||.|.|.:.|:.|::|||:.||||||||||.|.:.|
Zfish   253 ATQIFFSLSLAFGGLIAFSSYNPKKNDCERDALFVGIINSATSLYASIPIFAILGFKATSNFNSC 317

  Fly   359 VASNTEILVKNKLLGLND----TQGYEQAMSLLNGTE---LLRLQLSECSLAHELDNAAEGTGLA 416
            |.||  ||.......:.|    .:.|:..:..||.::   :..|.|..|.|.:.||.:|.|||||
Zfish   318 VNSN--ILDLTNAFDIGDRNITIENYDSWLRDLNASDPDRVSSLNLKHCVLKNFLDQSASGTGLA 380

  Fly   417 FIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKR-VKKQHVTGVVCL 480
            |||||:|::|:||:..||||||.||.||||.|..|.|||:|..|.|:.::.| :.|:..||::|:
Zfish   381 FIVFTEAVIEMPGSQVWAVLFFVMLFSLGLSSMFGNLEGVLTPLLDLHMVPRWMPKEIFTGLICV 445

  Fly   481 FCFIVGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRY 545
            ..|:|..||..|:|.|||::|:|:.|::.|:|:|..|:|||:..||.:||::||.||||.||..:
Zfish   446 VNFLVALIFTLGSGNYWLEIFNSYVGSVPLLVIAFFEIIAVVCFYGIKRFSDDIEQMTGRRPNLF 510

  Fly   546 WQWTWRYIGPVIMVCILVSSVVFMVIRNPTYGAWN---ADLGMIEQKSYPNWVMGIALSMILAGV 607
            |:..|..|.||:::.:||:.||..|.::|||.|||   .:....|:|.|..||..|.:.:....|
Zfish   511 WRCCWMGISPVMLLVVLVAYVVVQVQKHPTYPAWNPQYENFPETEEKPYSTWVFSICVLLSSVPV 575

  Fly   608 LPMPIVFLMR 617
            :.:|||.|.|
Zfish   576 ISIPIVALYR 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	276/574 (48%)
slc6a18	NP_001108369.2	None