Protein Alignment GstE11 and CLIC3

DIOPT Version :10

• Sequence 1: NP_611339.1
• Gene: GstE11 / 37128
• FlyBaseID: FBgn0034354
• Length: 225
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 49/207 - (23%)
• Similarity: 79/207 - (38%)
• Gaps: 52/207 - (25%)

  Fly    14 PPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHT-IPVLDDNGTIVSDSHIICSYLA 77
            |.|:.:.:.....|:...|..|:.:    :|.:.||..|..: :|:|..:....:|:..|..:|.
Human    23 PSCQRLFMVLLLKGVPFTLTTVDTR----RSPDVLKDFAPGSQLPILLYDSDAKTDTLQIEDFLE 83

  Fly    78 DKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSDRVAYLQKAYD 142
            :...|....||.|:..|.....:     |..|.|.  .||..|        ||:...|..|:...
Human    84 ETLGPPDFPSLAPRYRESNTAGN-----DVFHKFS--AFIKNP--------VPAQDEALYQQLLR 133

  Fly   143 G-----------LEHCLAEGD---------YLVGDKLTIADLSCIASVSTAEAF------APIEP 181
            .           |||.|| |:         :|.||:||:||.|.:..:...:..      |||
Human   134 ALARLDSYLRAPLEHELA-GEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQAPI-- 195

  Fly   182 DQFPRLVQWVKR 193
               |..::.|:|
Human   196 ---PAELRGVRR 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_611339.1	GST_N_Delta_Epsilon	5..78	CDD:239343	14/64 (22%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	31/126 (25%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		14/68 (21%)
		O-ClC	5..229	CDD:129941	49/207 (24%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		1/1 (100%)