Protein Alignment GstE11 and CLIC6

DIOPT Version :10

• Sequence 1: NP_611339.1
• Gene: GstE11 / 37128
• FlyBaseID: FBgn0034354
• Length: 225
• Species: Drosophila melanogaster
• Sequence 2: NP_001303938.1
• Gene: CLIC6 / 54102
• HGNCID: 2065
• Length: 704
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 39/181 - (21%)
• Similarity: 69/181 - (38%)
• Gaps: 40/181 - (22%)

  Fly    27 GLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHIICSYLADKYAPEGDDSLYPK 91
            |:..::..|::|   .|.|:...|......|.:..:|.:.:|.:.|..:|.:|.||.....|..:
Human   501 GVIFNVTTVDLK---RKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQ 562

  Fly    92 DPE----------------KRRLVDARLYYDCGHLFPRIR----FIVEPVIYFGAGEVPSDRVAY 136
            .||                |....||...:: .:|...:|    ::..|        :|.:..||
Human   563 HPESNSAGNDVFAKFSAFIKNTKKDANEIHE-KNLLKALRKLDNYLNSP--------LPDEIDAY 618

  Fly   137 LQKAYDGLEHCLAEG-DYLVGDKLTIADLSCIASVSTAEAFAPIEPD-QFP 185
                  ..|.....| .:|.||:||:||.:.:..:...:..|....| :||
Human   619 ------STEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_611339.1	GST_N_Delta_Epsilon	5..78	CDD:239343	11/50 (22%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	23/114 (20%)
CLIC6	NP_001303938.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..446
		PRK07764	<9..382	CDD:236090
		13 X 10 AA tandem repeat of G-D-[SNG]-[VIM]-[DEQ]-A-[EAG]-[GDVE]-[PRG]-[LAVP]	157..282
		O-ClC	471..704	CDD:129941	39/181 (22%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Y696	487..490