DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE11 and CLIC5

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001107558.1	Gene:	CLIC5 / 53405	HGNCID:	13517	Length:	410	Species:	Homo sapiens

Alignment Length:	170	Identity:	37/170 - (21%)
Similarity:	63/170 - (37%)	Gaps:	35/170 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHIICSYLADKYAPEGDDSLYPK 91
            |:..::..|::|   .|.|:...|......|.|..||.:.:|.:.|..:|.:...||    .|||
Human   205 GVVFNVTTVDLK---RKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPE----KYPK 262

  Fly    92 DPEKRRL-----VDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSDRVAYLQKAYDGLEHCLAE- 150
            ...|.|.     :|         :|.:....::.........:.......|:|..|.|...|.|
Human   263 LAAKHRESNTAGID---------IFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEE 318

  Fly   151 ------GD-------YLVGDKLTIADLSCIASVSTAEAFA 177
                  |:       :|.||:||:||.:.:..:...:..|
Human   319 IDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVA 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	37/170 (22%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	13/50 (26%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	19/103 (18%)
CLIC5	NP_001107558.1	O-ClC	173..408	CDD:129941	37/170 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154565
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930