DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE11 and GstD7

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	222	Identity:	79/222 - (35%)
Similarity:	125/222 - (56%)	Gaps:	9/222 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHI 71
            ||..|.:|..||:.:.|.||||||:.:|:|...|:....||:::|.|||||.|.|||.::.:|..
  Fly     6 LYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVIWESRA 70

  Fly    72 ICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIR---FIVEPVIYFGAGEVPSDR 133
            |..||.:||. :.|..|||.||:||.|::.|||:|.|.|:..:.   |::.....||..|. .|:
  Fly    71 IAVYLVEKYG-KPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFGDQEA-LDK 133

  Fly   134 VAYLQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFPRLVQWVKRIQALP 198
            |   ..|:..|...|...|::.|.:||:||:..:|:|||.|.|: .:..:||.:.:|:|....:.
  Fly   134 V---NSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWFS-FDLSKFPNVERWLKNAPKVT 194

  Fly   199 YYQKNNQEGLDMLVGLVKGLLAERQQK 225
            ...:.|.|.|......::.|.|.::::
  Fly   195 PGWEQNLESLQQGKKFLQDLQAAKEKE 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	74/193 (38%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	32/70 (46%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	37/119 (31%)
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	32/70 (46%)
		GstA	6..188	CDD:223698	73/187 (39%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	37/118 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460339
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800