DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE11 and GstD6

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_524915.1	Gene:	GstD6 / 48339	FlyBaseID:	FBgn0010042	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	198	Identity:	74/198 - (37%)
Similarity:	114/198 - (57%)	Gaps:	5/198 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHI 71
            ||....||..|||::||.|:|:|.:...||...||.....|:|:|.|||||.|.||..::.::..
  Fly     3 LYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDNLFVIWETRA 67

  Fly    72 ICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSDRVAY 136
            |..||.::|..  |||||||||:|:.|::.|||:|.|.|:..|.....|::..|.... .:.:..
  Fly    68 IVVYLVEQYGK--DDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLLRTGKPGT-QENLEK 129

  Fly   137 LQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFPRLVQWVKRIQAL-PYY 200
            |..|:|.|.:.|...||:.|::|::||:..:|:|||.| ....:..:||.:.:|.|..|.: |.:
  Fly   130 LNAAFDLLNNFLDGQDYVAGNQLSVADIVILATVSTTE-MVDFDLKKFPNVDRWYKNAQKVTPGW 193

  Fly   201 QKN 203
            .:|
  Fly   194 DEN 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	72/191 (38%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	30/70 (43%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	34/111 (31%)
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	30/70 (43%)
		PLN02395	11..208	CDD:166036	70/190 (37%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	34/111 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460326
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800