DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE11 and GstE12

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	223	Identity:	110/223 - (49%)
Similarity:	152/223 - (68%)	Gaps:	1/223 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AKPILYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVS 67
            :||.||||..|||.|||||||.|:||:|:||.:|:..|||.:.||||||.|||||.|.|....:.
  Fly     2 SKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATII 66

  Fly    68 DSHIICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSD 132
            |||.||:||.:||. :.:..||||:..:|..|||||:.|.||||.|:||:.||::|:|:.:...|
  Fly    67 DSHAICAYLVEKYG-QKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSID 130

  Fly   133 RVAYLQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFPRLVQWVKRIQAL 197
            ::||:||.::.||..|.:..||.|..|||||...:|:|::....|||:..:||::..|:||:..|
  Fly   131 KIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAEL 195

  Fly   198 PYYQKNNQEGLDMLVGLVKGLLAERQQK 225
            ||||:.|.:|.|.|..:.|..|||.:.|
  Fly   196 PYYQEVNGDGADELKSIFKAKLAENRGK 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	95/192 (49%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	45/72 (63%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	52/116 (45%)
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	45/72 (63%)
		GstA	6..201	CDD:223698	99/195 (51%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	52/117 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467995
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800