DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE11 and GstE8

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	87/215 - (40%)
Similarity:	127/215 - (59%)	Gaps:	3/215 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AKPILYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVS 67
            :|.|||....|||.||..||.||||:..:...:|..|.|..|.|||:.|.|||:|.|:|:|..:.
  Fly     2 SKLILYGTEASPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIW 66

  Fly    68 DSHIICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPR-IRFIVEPVIYFGAGEVPS 131
            |||.|.:||..||..  .|:|||||..:|.:||.||:::.|.:|.. :|.|.:|:...|...:|.
  Fly    67 DSHAISAYLVSKYGQ--SDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLFATGQTTIPK 129

  Fly   132 DRVAYLQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFPRLVQWVKRIQA 196
            :|...:.:.||.:|..|...|::.||:|||||.|.|.|::....|..|:..::..:..|:|||:.
  Fly   130 ERYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYANITAWIKRIEE 194

  Fly   197 LPYYQKNNQEGLDMLVGLVK 216
            ||||::...:|...||.|:|
  Fly   195 LPYYEEACGKGARDLVTLLK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	77/193 (40%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	35/72 (49%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	39/117 (33%)
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	77/193 (40%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	35/72 (49%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	39/117 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468019
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800