DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE11 and clic1

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_997847.1	Gene:	clic1 / 324481	ZFINID:	ZDB-GENE-030131-3202	Length:	241	Species:	Danio rerio

Alignment Length:	145	Identity:	31/145 - (21%)
Similarity:	54/145 - (37%)	Gaps:	38/145 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNA--QHTIPVLDDN---GTIVS--- 67
            ||...|.....||   ||::                |.|.:|  :::.|.::||   |.:.:
Zfish    94 PRLAACNPESNTA---GLDV----------------FSKFSAYIKNSNPQMNDNLEKGLLKALKK 139

  Fly    68 -DSHIICSYLADKYAPEGDDSLYPKDPEKRRLVDAR--LYYDCGHLFPRIRFIVEPVIYFGAGEV 129
             |.: :.|.|.|:......|.:.   ...|..:|.:  ...|| :|.|::..:....:.|....:
Zfish   140 LDDY-LSSPLPDEIDENSADDVI---SSTRSFLDGQELTLADC-NLLPKLHIVKVVCLKFRGFSI 199

  Fly   130 PSDRVA---YLQKAY 141
            |....:   ||..||
Zfish   200 PRSLTSLWRYLDAAY 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	31/145 (21%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	17/75 (23%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	12/53 (23%)
clic1	NP_997847.1	GST_N_CLIC	3..93	CDD:239359
		O-ClC	6..241	CDD:129941	31/145 (21%)
		GST_C_CLIC1	100..238	CDD:198333	28/139 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589708
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930