Protein Alignment GstE11 and GSTA4

DIOPT Version :10

• Sequence 1: NP_611339.1
• Gene: GstE11 / 37128
• FlyBaseID: FBgn0034354
• Length: 225
• Species: Drosophila melanogaster
• Sequence 2: NP_001503.1
• Gene: GSTA4 / 2941
• HGNCID: 4629
• Length: 222
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 53/217 - (24%)
• Similarity: 100/217 - (46%)
• Gaps: 26/217 - (11%)

  Fly     1 MSAKPILYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTI 65
            |:|:|.|:|........:|....||.|:|.|...:..|...:|..:...|..|. :|:::.:|..
Human     1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQ-VPMVEIDGMK 64

  Fly    66 VSDSHIICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVP 130
            :..:..|..|:|||:      :|:.|:.::|.|:|  :|.: |.|......|:.|.:      .|
Human    65 LVQTRSILHYIADKH------NLFGKNLKERTLID--MYVE-GTLDLLELLIMHPFL------KP 114

  Fly   131 SDR----VAYLQKA---YDGLEHCLAEG---DYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFP 185
            .|:    |...|||   |..:...:..|   .:|||::|::||:..:.::...|...|.....||
Human   115 DDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFP 179

  Fly   186 RLVQWVKRIQALPYYQKNNQEG 207
            .|.::..::..:|..::..:.|
Human   180 FLQEYTVKLSNIPTIKRFLEPG 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_611339.1	GST_N_Delta_Epsilon	5..78	CDD:239343	17/72 (24%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	29/124 (23%)
GSTA4	NP_001503.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..82	CDD:469754	20/84 (24%)
		GST_C_Alpha	86..220	CDD:198317	29/125 (23%)