DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE11 and gst2

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	227	Identity:	64/227 - (28%)
Similarity:	90/227 - (39%)	Gaps:	37/227 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDD---NGTIVSD 68
            ||.....|....|:|....|.|..:....:.:.||.|..|.|.||....:|.|.|   |...:.:
pombe     6 LYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNNDYTIWE 70

  Fly    69 SHIICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAG------ 127
            |..|..||||||..:...||...|||..:|:....:...|          :.||:..||
pombe    71 SDAILIYLADKYDTDRKISLSFDDPEYYKLIQYLFFQASG----------QGVIWGQAGWFNFFH 125

  Fly   128 --EVPSDRVAY---LQKAYDGLEHCLAEGDYLVGDKLTIADLSCI------------ASVSTAEA 175
              .|.|....|   :::....||..|.:.||||.:|.||||||.|            ...|..|.
pombe   126 HEPVVSAVTRYRNEIKRVLGVLEDILKDRDYLVANKYTIADLSFIPWNYNLGGLFGEGKFSFKEE 190

  Fly   176 FAPIE-PDQFPRLVQWVKRIQALPYYQKNNQE 206
            ...:: ..:||:...|.:|:.|.|..:...:|
pombe   191 VPQLDFEKEFPKAYAWNQRLLARPAVKATFEE 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	62/217 (29%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	22/73 (30%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	34/137 (25%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	26/77 (34%)
		GstA	5..226	CDD:223698	64/227 (28%)
		GST_C_Ure2p	96..219	CDD:198326	33/132 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	8	7.760