DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE11 and Clic6

DIOPT Version :9

Sequence 1:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_766057.1	Gene:	Clic6 / 209195	MGIID:	2146607	Length:	596	Species:	Mus musculus

Alignment Length:	180	Identity:	35/180 - (19%)
Similarity:	70/180 - (38%)	Gaps:	38/180 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHIICSYLADKYAPEGDDSLYPK 91
            |:..::..|::|   .|.|:...|......|.:..:|.:.:|.:.|..:|.:|..|.....|..:
Mouse   393 GVIFNVTTVDLK---RKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQ 454

  Fly    92 DPE----------------KRRLVDARLYYDCGHLFPRIR----FIVEPVIYFGAGEVPSDRVAY 136
            .||                |....||...|: .:|...::    ::..|:    ..|:.:|
Mouse   455 HPESNSAGNDVFAKFSAFIKNTKKDANEIYE-KNLLRALKKLDSYLNSPL----PDEIDAD---- 510

  Fly   137 LQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPD-QFP 185
                 ...:..:::..:|.||:||:||.:.:..:...:..|....| :||
Mouse   511 -----SSEDVTVSQRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFP 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	35/180 (19%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	11/50 (22%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	20/113 (18%)
Clic6	NP_766057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..360
		PHA02664	<69..167	CDD:177447
		GST_N_CLIC	360..448	CDD:239359	13/57 (23%)
		O-ClC	363..596	CDD:129941	35/180 (19%)
		GST_C_CLIC6	455..594	CDD:198334	21/115 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844594
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930