Protein Alignment CG30116 and MDV1

DIOPT Version :10

• Sequence 1: NP_725799.1
• Gene: CG30116 / 37126
• FlyBaseID: FBgn0028496
• Length: 1922
• Species: Drosophila melanogaster
• Sequence 2: NP_012423.1
• Gene: MDV1 / 853332
• SGDID: S000003648
• Length: 714
• Species: Saccharomyces cerevisiae
• Alignment Length: 667
• Identity: 149/667 - (22%)
• Similarity: 249/667 - (37%)
• Gaps: 209/667 - (31%)

  Fly   951 SDSELLLTGSEDATVLVWHVGLRERRAHIKNAHTAPITGVAAGANNTLIISSSEDASIAITDLAS 1015
            :|.:||..|.|:.       .||      ||| :...|.:..|..:.|.|     |.:||.:
Yeast   123 ADGKLLTEGGENE-------NLR------KNA-SKKETSLFQGFKSYLPI-----AELAIEN--- 165

  Fly  1016 GKLRHRITHHRGPVSGIVVAGACDVLISGGLDRTICVWDLDNF---------------------- 1058
               ..|:.:.....||.|  ||.||: |...:|.....:|.||
Yeast   166 ---TERLNYDTNGTSGTV--GAKDVM-SKTNERDEIHTELPNFQDSFLIPPGVETKKISSSYSPS 224

  Fly  1059 -------TLLNTMQMTSAVLRIDISWNSVFLLALCEDNALYVRTLATGKELHTLKGHKSKIRSIS 1116
                   ||:|:::.      ::|..||    .|.|...:.|       |:..|:..|.|:
Yeast   225 ALKSFSQTLVNSLEF------LNIQKNS----TLSEIRDIEV-------EVENLRQKKEKL---- 268

  Fly  1117 IGKDSQRCVVGCDDTRALIYDMHAGKLVRSLPPNPGPVTAVHAMDNDDFLVTVGGNKITFYSFRN 1181
            :||     :...:..:.|:.|                 ......|..|||...|...|...|..|
Yeast   269 LGK-----IANIEQNQLLLED-----------------NLKQIDDRLDFLEEYGLEVIEANSDEN 311

  Fly  1182 EELYVNPYSRHPRRKRSLKRHA--------QAQRSPSTTLPPITCFDLSRDSQQM---------- 1228
            .|      ......:::||..|        ::..|.::.|||       |..||:
Yeast   312 AE------DDGMSERKALKNDAIRNEGVTTESISSEASNLPP-------RRRQQLRDDNSLNRLG 363

  Fly  1229 ---AIASGRHVHLMRINTPEYQ----------CTLEGHTAGVSCLKF-APNGEFLATGSEDRLVH 1279
               :.:..||    |.:.|.:|          ..:..|...::||.| ||.|.....|..|..|.
Yeast   364 AFYSKSKKRH----RKSFPTFQQLYEPGTKIGSIMSTHDDFLTCLDFDAPFGTLCTAGYLDHTVK 424

  Fly  1280 IWNLA----LGEICNSFKGHTAPVVKVVVLMDSLRVISTDRDSMLLVWMAHSGNLLQTIQGPYKS 1340
            ||:|:    :||:.    ||.|.:..:.:..|...:::..||:.|.:|   :.||.|.:....::
Yeast   425 IWDLSKQNKIGELA----GHLATINCMQINRDYGTLVTGGRDAALKLW---NLNLAQQLYQETQN 482

  Fly  1341 L-SVTNNMRFAVSTNGDNTLKIWSLTQEDEKYSVSHSDEITCFEISADSVHIISGSRDMSLKVWQ 1404
            | |.||:    :.:...:|.:             :|:||:|.  :|.|...::|||:|.:::.|.
Yeast   483 LTSPTNH----IDSPCVHTFE-------------AHTDEVTA--LSLDPSFLVSGSQDRTIRQWD 528

  Fly  1405 ATGGKLSQ--------VLVGHSDAVTCVAVSVTNKTQ-------------VLSGSKDMNLILWDL 1448
            ...||..|        ||...::.....:..:|.:.:             :.:|:||..:.||||
Yeast   529 LRSGKCLQTIDLSFANVLTTSTNVDLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDL 593

  Fly  1449 LTGEEVHTLAGHLGPVIGVKVSADGSTAVSGSDDKTLIVWETKRGLALTSLQMHVPFTHFDISLE 1513
            .:|:.:.||.||...:..:|.  |.:..|:||.|:|:.:|:.:.||.........|....|:..|
Yeast   594 RSGKVIRTLKGHTDAITSLKF--DSACLVTGSYDRTVRIWDLRTGLLNKFHAYSAPVLSLDLFQE 656

  Fly  1514 VSRVL------VQLVDS 1524
            .:.|:      ||:.||
Yeast   657 NAAVVVADEPSVQIYDS 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30116	NP_725799.1	WD40	<897..1057	CDD:441893	28/105 (27%)
		WD40 repeat	901..937	CDD:293791
		WD40 repeat	942..982	CDD:293791	8/30 (27%)
		WD40 repeat	988..1024	CDD:293791	8/35 (23%)
		WD40	991..1491	CDD:441893	128/586 (22%)
		WD40 repeat	1029..1064	CDD:293791	15/63 (24%)
		WD40 repeat	1071..1106	CDD:293791	7/34 (21%)
		WD40 repeat	1112..1147	CDD:293791	4/34 (12%)
		WD40 repeat	1216..1252	CDD:293791	8/58 (14%)
		WD40 repeat	1258..1294	CDD:293791	14/40 (35%)
		WD40 repeat	1299..1335	CDD:293791	8/35 (23%)
		WD40 repeat	1340..1374	CDD:293791	5/34 (15%)
		WD40 repeat	1379..1415	CDD:293791	12/43 (28%)
		WD40 repeat	1421..1458	CDD:293791	10/49 (20%)
		WD40 repeat	1464..1488	CDD:293791	7/23 (30%)
MDV1	NP_012423.1	Mdv1_N	97..298	CDD:467856	51/245 (21%)
		Mdv1	123..171	CDD:402923	18/72 (25%)
		WD40	397..713	CDD:238121	78/305 (26%)
		WD40 repeat	402..439	CDD:293791	14/40 (35%)
		WD40 repeat	444..499	CDD:293791	13/61 (21%)
		WD40 repeat	506..539	CDD:293791	11/34 (32%)
		WD40 repeat	546..603	CDD:293791	11/56 (20%)
		WD40 repeat	648..683	CDD:293791	7/26 (27%)
		WD40 repeat	690..712	CDD:293791