DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30116 and Wdsub1

DIOPT Version :10

Sequence 1:NP_725799.1 Gene:CG30116 / 37126 FlyBaseID:FBgn0028496 Length:1922 Species:Drosophila melanogaster
Sequence 2:NP_001366327.1 Gene:Wdsub1 / 72137 MGIID:1919387 Length:475 Species:Mus musculus


Alignment Length:404 Identity:99/404 - (24%)
Similarity:158/404 - (39%) Gaps:93/404 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1250 LEGHTAGVSCLKFAPNGEFLATGSEDRLVHIWNLALGEICNSFKGHT---------APVVKVVVL 1305
            |:.||..|.|..|:|:|..||:.|.|....:|        :|..|||         :||......
Mouse    50 LKFHTYAVHCCCFSPSGHVLASCSTDGTTVLW--------SSHSGHTLTVLEQPGGSPVRVCCFS 106

  Fly  1306 MDSLRVISTDRDSMLLVWMAHS-----------GNLLQTIQGPYKSLSVTNNMRFAVSTNGDNTL 1359
            .||..:.|...|..:.:|.|.:           .:|:.....|...|.||.      |:.||  |
Mouse   107 PDSAYLASGAADGSIALWNAQTYKLYRCGSVKDSSLVACAFSPDGGLFVTG------SSGGD--L 163

  Fly  1360 KIWSLTQEDEKYSVSHSDE-----ITCFEISA---------DSVHIISGSRDMSLKVWQAT---- 1406
            .:|     |::....||::     |||...|:         .|..:.|..:|..:|:|..|    
Mouse   164 TVW-----DDRMRCLHSEKAHDLGITCCSFSSQPLSGGEGLQSYQLASCGQDCEIKLWAVTITRV 223

  Fly  1407 -GGKL--SQVLVGHSDAVTCVAVSVTNKTQVLSGSKDMNLILWDLLTGEEVHTLAGHLGPVIGVK 1468
             |.:|  ...|.||...|...|.|...| .:.|||.|.::|:..:.....:|||..|...|....
Mouse   224 LGFELKYKSTLSGHCAPVLACAFSHDGK-MLASGSVDKSVIIHGIGPQSVLHTLTQHTRYVTTCA 287

  Fly  1469 VSADGSTAVSGSDDKTLIVWETKRGLALTSLQMHVPFTHF-------DISLEV-SRVLVQLVDSY 1525
            .:.:.....:||.|||:.:|:........:..|:.|..||       |:|:.: ::.|..||..:
Mouse   288 FAPNTLLLATGSMDKTVNIWQFDLETPCQAGSMNDPLKHFTEEWSEEDVSVWLRAQGLEDLVGIF 352

  Fly  1526 NLPVI----CLHNTP---AQYVKLPTYSGPSK---DVEDLR----------PQGPKRQMKRLLKK 1570
            ....|    .||.|.   |..:|:.:....||   .:|:||          |......:.|.|.|
Mouse   353 RANNIDGKELLHLTKESLAGDLKIESLGLRSKVLRSIEELRAKMDSLSSGIPDEFICPITRELMK 417

  Fly  1571 E--VSLDTYTWQKK 1582
            :  ::.|.|:::::
Mouse   418 DPVIASDGYSYERE 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30116NP_725799.1 WD40 <897..1057 CDD:441893
WD40 repeat 901..937 CDD:293791
WD40 repeat 942..982 CDD:293791
WD40 repeat 988..1024 CDD:293791
WD40 991..1491 CDD:441893 73/281 (26%)
WD40 repeat 1029..1064 CDD:293791
WD40 repeat 1071..1106 CDD:293791
WD40 repeat 1112..1147 CDD:293791
WD40 repeat 1216..1252 CDD:293791 1/1 (100%)
WD40 repeat 1258..1294 CDD:293791 10/35 (29%)
WD40 repeat 1299..1335 CDD:293791 8/46 (17%)
WD40 repeat 1340..1374 CDD:293791 9/33 (27%)
WD40 repeat 1379..1415 CDD:293791 12/51 (24%)
WD40 repeat 1421..1458 CDD:293791 11/36 (31%)
WD40 repeat 1464..1488 CDD:293791 6/23 (26%)
Wdsub1NP_001366327.1 WD40 <3..310 CDD:441893 73/281 (26%)
WD 1 10..47
WD40 repeat 16..52 CDD:293791 1/1 (100%)
WD 2 52..91 16/46 (35%)
WD40 repeat 57..93 CDD:293791 14/43 (33%)
WD 3 95..134 8/38 (21%)
WD40 repeat 101..136 CDD:293791 6/34 (18%)
WD 4 137..176 12/51 (24%)
WD40 repeat 143..177 CDD:293791 12/46 (26%)
WD 5 178..227 11/48 (23%)
WD40 repeat 183..235 CDD:293791 12/51 (24%)
WD 6 236..275 11/39 (28%)
WD40 repeat 241..264 CDD:293791 8/23 (35%)
WD40 repeat 283..307 CDD:293791 6/23 (26%)
SAM_WDSUB1 327..398 CDD:188904 17/70 (24%)
U-box 403..475 CDD:398320 6/29 (21%)
Blue background indicates that the domain is not in the aligned region.

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