DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30116 and wda

DIOPT Version :9

Sequence 1:	NP_725799.1	Gene:	CG30116 / 37126	FlyBaseID:	FBgn0028496	Length:	1922	Species:	Drosophila melanogaster
Sequence 2:	NP_651136.1	Gene:	wda / 42750	FlyBaseID:	FBgn0039067	Length:	743	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	68/314 - (21%)
Similarity:	126/314 - (40%)	Gaps:	58/314 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1189 YSRHPRRKRSLKRHAQAQRSPST----TLPPITCFDLSRDSQQMAIASGRHVHLMRINTPEY-QC 1248
            |.|:|:::...:.:..|.:...|    :...:.|.:..|..:..|    ||......:..|| ..
  Fly   431 YRRYPQKRCPWELNNCANQEEETDEDSSDEDVKCSEEERRERNRA----RHCKYADNSYNEYGGF 491

  Fly  1249 TLEGHTAGVSCLKFAPNGEFLATGSEDRLVHIW---NLALGEICNSFKGHTAPVVKVVVLMDSLR 1310
            .|.|||.||:.::|:.:...:.:.|:|..:..|   ||....|   ::.|..|
  Fly   492 QLRGHTKGVTDVRFSAHYPLMYSVSKDATMRCWRAHNLHCAAI---YRSHNYP------------ 541

  Fly  1311 VISTDRDSMLLVWMAHSGNLLQTIQGPYKSLSVTNNMRFAVSTNGDNTLKIWSLTQEDEK--YSV 1373
                       :|......:.|                :.|:.:.|.:.::|||.:|...  |:
  Fly   542 -----------IWCLDESPVGQ----------------YVVTGSKDLSARLWSLEKEHALIIYA- 578

  Fly  1374 SHSDEITCFEISADSVHIISGSRDMSLKVWQATGGKLSQVLVGHSDAVTCVAVSVTNKTQVLSGS 1438
            .|:.::.|.....:..:|.:||.|.|:::|.||.|||.:|......|||.:|.|...|....:|
  Fly   579 GHTQDVECVAFHPNGNYIATGSADHSVRLWCATSGKLMRVFADCRQAVTQLAFSPDGKMLAAAG- 642

  Fly  1439 KDMNLILWDLLTGEEVHTLAGHLGPVIGVKVSADGSTAVSGSDDKTLIVWETKR 1492
            ::..:.::||..|.::..|..|...:..:..|.......:...|.||.:|:.|:
  Fly   643 EETKVRIFDLAAGAQLAELKDHSASISSLSWSTHNRHLATACSDGTLRLWDIKK 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30116	NP_725799.1	AAA_16	359..505	CDD:289934
		WD40 repeat	901..937	CDD:293791
		WD40	933..1282	CDD:238121	22/100 (22%)
		WD40 repeat	942..982	CDD:293791
		WD40 repeat	988..1024	CDD:293791
		WD40	1022..1484	CDD:225201	64/304 (21%)
		WD40 repeat	1029..1064	CDD:293791
		WD40 repeat	1071..1106	CDD:293791
		WD40 repeat	1112..1147	CDD:293791
		WD40 repeat	1216..1252	CDD:293791	8/36 (22%)
		WD40	1248..1502	CDD:238121	56/250 (22%)
		WD40 repeat	1258..1294	CDD:293791	7/38 (18%)
		WD40 repeat	1299..1335	CDD:293791	2/35 (6%)
		WD40 repeat	1340..1374	CDD:293791	7/35 (20%)
		WD40 repeat	1379..1415	CDD:293791	13/35 (37%)
		WD40 repeat	1421..1458	CDD:293791	9/36 (25%)
		WD40 repeat	1464..1488	CDD:293791	4/23 (17%)
wda	NP_651136.1	TAF5_NTD2	104..273	CDD:298747
		WD40	324..>700	CDD:225201	68/314 (22%)
		WD40	491..700	CDD:238121	56/250 (22%)
		WD40 repeat	501..537	CDD:293791	7/38 (18%)
		WD40 repeat	542..578	CDD:293791	8/51 (16%)
		WD40 repeat	585..619	CDD:293791	12/33 (36%)
		WD40 repeat	626..662	CDD:293791	9/36 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900