DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rswl and Trmt10c

DIOPT Version :9

Sequence 1:	NP_611335.1	Gene:	rswl / 37124	FlyBaseID:	FBgn0034351	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_083368.1	Gene:	Trmt10c / 52575	MGIID:	1196261	Length:	414	Species:	Mus musculus

Alignment Length:	424	Identity:	135/424 - (31%)
Similarity:	207/424 - (48%)	Gaps:	49/424 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKHFAR-------WRLGSQLLKGCAAPVRQASKTSSAENLIAGTEE----PQKKFVNPF-SQPAP 54
            |:.|||       .|..|.|..|    |.|...:|.|.:|....::    |::..::.: :....
Mouse     8 LRPFARCLVPYTFHRKRSHLYSG----VLQRYMSSKAPSLSCHNKDSASPPEQLELDGWKATMKS 68

  Fly    55 ALSNDTISENKEERDKRLKVLQLEADIAHQEGRRVPSLEFFKDHHWEHVLTLPTKSARIKYFGYL 119
            ::..|.:||..::.:..|...:...::....|:.||  |...:...:.::...:|||:.||..||
Mouse    69 SIQEDGVSEVSDKDEDSLASTRELIEMWRLLGKEVP--EHITEEDLKTLMECASKSAKKKYLRYL 131

  Fly   120 WQIEMKKEADQRK---KAERAKEAER-RVAEMRKEREENTHIIYGLGHTSLFLRIYDTTIN---H 177
            :..|..|:|.|.|   |||..:||:| |:.|...|.::...         :|||::|..||   .
Mouse   132 YGKEKAKKAKQVKKEMKAEAREEAKRARLLETTAEEQQQDF---------MFLRLWDRQINIALG 187

  Fly   178 WQNNRLTRAMQFAPKMVLDCSYDEHMNNREATYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRC 242
            |:.   .:||||...:|.|.:||.:|...|......||:.....||.|.:||.:::||.::||..
Mouse   188 WKG---VQAMQFGQPLVFDMAYDNYMKPSELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDSAY 249

  Fly   243 MQSL-QRYIPTMHNPEFPINLHSKCFTELFPKQNLVYLTPHCREDLVTYNPDDIYIVGAMVDTMN 306
            .:.| :||....  .:..:....|...:||||.:::|||......:.|:..|.|||:|:.||...
Mouse   250 HRELVKRYREKW--DKLLLTATEKSPVDLFPKDSIIYLTADSPNVMTTFKHDKIYIIGSFVDKNT 312

  Fly   307 NEPLSLAKAKRLGLRMARLPLDRYLQWGSGSGKSLTLNQMINIMLDLKKTGDWDTALKHVPRRKV 371
            ....||||||||.:....||||:||||..|: |:|||:|||.|:|.||.||:|:.|||.|||||.
Mouse   313 QTGTSLAKAKRLNIATECLPLDKYLQWEIGN-KNLTLDQMIRILLCLKNTGNWEEALKFVPRRKH 376

  Fly   372 V--------QNEFQPRREKDHWSTGTRARKLNMR 397
            .        ..|...:.:|.......|...||:|
Mouse   377 TGYLEVSEQSQELVRKLKKTKTLNSFRKGSLNVR 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rswl	NP_611335.1	tRNA_m1G_MT	201..370	CDD:294285	69/169 (41%)
Trmt10c	NP_083368.1	tRNA_m1G_MT	208..375	CDD:280003	69/169 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837926
Domainoid	1	1.000	126	1.000	Domainoid score	I5429
eggNOG	1	0.900	-	-		E1_KOG2967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9858
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4114
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46657
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006087
OrthoInspector	1	1.000	-	-		oto93153
orthoMCL	1	0.900	-	-		OOG6_107771
Panther	1	1.100	-	-	LDO	PTHR13563
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1545
SonicParanoid	1	1.000	-	-		X5012
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790