DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rswl and Trmt10c

DIOPT Version :9

Sequence 1:	NP_611335.1	Gene:	rswl / 37124	FlyBaseID:	FBgn0034351	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001008338.1	Gene:	Trmt10c / 304012	RGDID:	1306333	Length:	414	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	119/367 - (32%)
Similarity:	176/367 - (47%)	Gaps:	52/367 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PVRQASKTSSAENL-IAGTEEPQKKFVNPFSQPAPALSNDTISENKEERDKRLKVLQLEADIAHQ 84
            |......||..|.| :.|.:...|.          ::..:.:|...::.:..|...:...::...
  Rat    44 PCHNKDSTSPPEQLELDGWKTTMKS----------SIQENGVSVVSDKDEDSLAATRELIEMWRL 98

  Fly    85 EGRRVPSLEFFKDHHWEHVLTLPTKSARIKYFGYLWQIEMKKEADQRKKAERAKEAERRVAEMRK 149
            .|:.||  |...:...:.::...:|||:.||..||:..||.|:|.|.||  ..|.|.|..|:..:
  Rat    99 LGKEVP--EHITEEELKTLMECASKSAKKKYLRYLYGKEMMKKAKQMKK--EMKAAAREEAKRAR 159

  Fly   150 EREENTHIIYGLGHTS---LFLRIYDTTIN---HWQNNRLTRAMQFAPKMVLDCSYDEHMNNREA 208
            ..|.:|      |...   :|||::|...|   .|:.   .:||||...:|.|.:||.:|...|.
  Rat   160 SLEPST------GEEQRDFMFLRLWDRQTNIALGWKG---VQAMQFGQPLVFDMAYDNYMKPSEL 215

  Fly   209 TYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRCMQSL-QRY---------IPTMHNPEFPINLH 263
            .....||:.....||.|.:||.:::||.::|....:.| :||         ..|..:|
  Rat   216 QNTVSQLLESEGWNRRNVDPFHIYFCNLEVDGAYHRELVKRYGEKWDKLLLTATEKSP------- 273

  Fly   264 SKCFTELFPKQNLVYLTPHCREDLVTYNPDDIYIVGAMVDTMNNEPLSLAKAKRLGLRMARLPLD 328
                .:||||.:::|||......:.|:..|.|||:|:.||.......|||||||..|....||||
  Rat   274 ----VDLFPKDSIIYLTADSPNVMTTFKHDKIYIIGSFVDKNTQTGTSLAKAKRQNLATECLPLD 334

  Fly   329 RYLQWGSGSGKSLTLNQMINIMLDLKKTGDWDTALKHVPRRK 370
            :||||..|: |:|||:|||.|:|.||.||:|:.|||.|||||
  Rat   335 KYLQWDVGN-KNLTLDQMIRILLCLKNTGNWEEALKFVPRRK 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rswl	NP_611335.1	tRNA_m1G_MT	201..370	CDD:294285	69/178 (39%)
Trmt10c	NP_001008338.1	tRNA_m1G_MT	208..375	CDD:280003	69/178 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341703
Domainoid	1	1.000	123	1.000	Domainoid score	I5499
eggNOG	1	0.900	-	-		E1_KOG2967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9858
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4097
OMA	1	1.010	-	-		QHG46657
OrthoDB	1	1.010	-	-		D1569668at2759
OrthoFinder	1	1.000	-	-		FOG0006087
OrthoInspector	1	1.000	-	-		oto96704
orthoMCL	1	0.900	-	-		OOG6_107771
Panther	1	1.100	-	-	LDO	PTHR13563
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5012
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770