DRSC/TRiP Functional Genomics Resources

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Protein Alignment slim and Klhdc2

DIOPT Version :9

Sequence 1:NP_523782.1 Gene:slim / 37121 FlyBaseID:FBgn0261477 Length:609 Species:Drosophila melanogaster
Sequence 2:NP_081393.2 Gene:Klhdc2 / 69554 MGIID:1916804 Length:406 Species:Mus musculus


Alignment Length:385 Identity:92/385 - (23%)
Similarity:142/385 - (36%) Gaps:81/385 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   164 SDKQQSQMAGQIPMYAFQPLRLVK--CQYRDKHIPGGFPLARSGHRIIASNSHLYSLGGYNPRSA 226
            :|..:...|..:|..||:....::  |           |..||||..::...|::..|||  :|.
Mouse     2 ADGNEDARAEDLPGPAFENYEAMELAC-----------PAERSGHVAVSDGRHMFVWGGY--KSN 53

  Fly   227 MSASRHGRCLLFQELWSYNFATRTWRLELNAGNAANMPVELASNALTIHNNVLISHGGTGYPFGV 291
            .....:...|..:|||.||..|..|: ::|  ...::|..::.:.....:.||...||..     
Mouse    54 QVRGLYDFYLPREELWIYNMETGRWK-KIN--TEGDVPPSMSGSCAVCVDRVLYLFGGHH----- 110

  Fly   292 SCSNDCYVYRTASAGATPGV--DRLQVKGDLPTAQYGPGIVIHKHFLYTIG-----------GTT 343
            |..|....|...|..|..|:  :|:..:|..|:::...|:.::|:.|...|           ||.
Mouse   111 SRGNTNKFYMLDSRSADRGLQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTF 175

  Fly   344 GFDYTC------------DVYRLDLRTGIWENVYISRP-EMRDDPEGRYRHEVVYDGKHIFVLGG 395
            .||.|.            .|:.||..|..|     |:| .....|..|..|.....|...||.||
Mouse   176 EFDETSFWNSSHPRGWNDHVHILDTETFAW-----SQPITTGKAPSPRAAHACATVGNKGFVFGG 235

  Fly   396 GTSHSVYDLQRIPAYNLEANCWDYFETYPDQRAADADDGNRGY-PKPRKCFSCVQHQSSTGDIEA 459
                ...|.:....:.|..:.|::.|..|           :|. |..|...|.....|.    ..
Mouse   236 ----RYRDARMNDLHYLNLDTWEWNELIP-----------QGVCPVGRSWHSLTPVSSD----HL 281

  Fly   460 FITGGLQGDFSTY---FSDIWKLNLRTKHWYRIETAILPRPLYFHSAAHSDNGCMYVFGG 516
            |:.||    |:|.   .||.|...:....|.:.....:.:|..:|:|..||.|.:.||||
Mouse   282 FLFGG----FTTEKQPLSDAWTYCISKNEWIQFNHPYVEKPRLWHTACASDEGEVIVFGG 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slimNP_523782.1 KELCH repeat 203..263 CDD:276965 18/59 (31%)
KELCH repeat 267..321 CDD:276965 12/55 (22%)
KELCH repeat 324..364 CDD:276965 14/62 (23%)
Kelch_1 325..372 CDD:279660 16/70 (23%)
Kelch_4 441..492 CDD:290154 12/53 (23%)
KELCH repeat 442..495 CDD:276965 12/55 (22%)
Klhdc2NP_081393.2 PLN02193 <29..296 CDD:177844 72/304 (24%)
KELCH repeat 32..91 CDD:276965 19/63 (30%)
Kelch 1 43..89 14/50 (28%)
KELCH repeat 92..138 CDD:276965 11/50 (22%)
Kelch 2 102..155 14/57 (25%)
Kelch 3 157..202 10/44 (23%)
KELCH repeat 218..265 CDD:276965 13/61 (21%)
Kelch 4 229..278 13/63 (21%)
Kelch_3 279..326 CDD:404319 12/54 (22%)
Kelch 5 280..329 13/52 (25%)
Kelch 6 331..377 4/7 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0379
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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