Protein Alignment slim and Rabepk

DIOPT Version :10

• Sequence 1: NP_523782.1
• Gene: slim / 37121
• FlyBaseID: FBgn0261477
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_663497.2
• Gene: Rabepk / 227746
• MGIID: 2139530
• Length: 380
• Species: Mus musculus
• Alignment Length: 375
• Identity: 68/375 - (18%)
• Similarity: 113/375 - (30%)
• Gaps: 133/375 - (35%)

  Fly   196 PGGFPLARSGHRII-------ASNSHLYSLGGYNPRSAMS--------------ASRHGRCLLFQ 239
            ||..|..|.||...       |.:..::.:||.||..:.|              |:|.|....::
Mouse    32 PGDRPCPRVGHSCSYFPPVGDAESGKIFIVGGANPNQSFSDVHTMDLGTHQWDTATREGLLPRYE 96

  Fly   240 -----------ELWSYNFA---------------TRTWRLELNAGNAANMPVELASNALTIHNNV 278
                       .:|.:..|               .|||......|:        ..:..|.|.:
Mouse    97 HASFLPSCSPHSIWVFGGADQSGNRNCLQVMSPEDRTWSTPEVTGS--------PPSPRTFHTS- 152

  Fly   279 LISHGGTGYPFGVSCSNDCYVYRTASAGATPGVD-RLQV-------------KGDLPTAQYGPGI 329
                       ..:..|..||:.....||.|..| :|.|             .|..|:.::|..:
Mouse   153 -----------SAAIGNQLYVFGGGERGAQPVEDVKLHVFDANTLTWSQPETHGSPPSPRHGHVM 206

  Fly   330 VIHKHFLYTIGGTTGFDYTCDVYRLDLRTGIWENVYISRPEMRDDPEGRYRHEVVYDGKHIFVLG 394
            |.....|:..||..|..:..|::.:|:....|:.:..:...    |.|...|..|..|.|:::.|
Mouse   207 VAAGTKLFIHGGLAGDKFFDDLHCIDIGDMSWQKLGPTGAV----PVGCAAHAAVAVGHHVYMFG 267

  Fly   395 GGTSHSVYDLQRIPAYNLEANCWDYFE-----------------------------------TYP 424
            |.|:...  |..:..|:.|...|...:                                   |..
Mouse   268 GMTATGA--LNMMYKYHTEKQHWTVLQFDTSLPAGRLDHSMCVIPWPVMSTSENKDSDSVILTLQ 330

  Fly   425 DQR--AADADDGNRGYPKPRKCFSCVQHQSSTGDIEAFITGGLQGDFSTY 472
            |::  ||:..:...|.|         ..:|.|..:..|:.||:..:...|
Mouse   331 DEKGDAAEKAETQSGGP---------HEESPTTVLLCFVFGGMNTEGEVY 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slim	NP_523782.1	NanM	197..516	CDD:442289	67/374 (18%)
		KELCH repeat	203..263	CDD:276965	18/106 (17%)
		KELCH repeat	267..321	CDD:276965	12/67 (18%)
		KELCH repeat	324..364	CDD:276965	9/39 (23%)
		KELCH repeat	442..495	CDD:276965	6/31 (19%)
Rabepk	NP_663497.2	NanM	21..274	CDD:442289	52/265 (20%)
		Kelch 1	57..103		8/45 (18%)
		KELCH repeat	94..143	CDD:276965	6/56 (11%)
		Kelch 2	108..154		8/65 (12%)
		KELCH repeat	147..198	CDD:276965	12/62 (19%)
		Kelch 3	159..211		12/51 (24%)
		KELCH repeat	201..243	CDD:276965	9/41 (22%)
		Kelch 4	212..258		10/49 (20%)
		KELCH repeat	251..291	CDD:276965	11/41 (27%)
		Kelch 5	262..311		8/50 (16%)
		Kelch	264..309	CDD:128874	7/46 (15%)
		Kelch 6	357..380		4/15 (27%)