Protein Alignment slim and Fbxo42

DIOPT Version :10

• Sequence 1: NP_523782.1
• Gene: slim / 37121
• FlyBaseID: FBgn0261477
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_766106.2
• Gene: Fbxo42 / 213499
• MGIID: 1924992
• Length: 717
• Species: Mus musculus
• Alignment Length: 342
• Identity: 81/342 - (23%)
• Similarity: 132/342 - (38%)
• Gaps: 87/342 - (25%)

  Fly   100 MDAASDLDEEEEEEDDDVDVDVDYGDTDSESEFEEMYSDEWTSSSDELDEG------TELSKSVL 158
            |.::||      .|||.| :.||..:|..|...|:   ||......|::|.      :||.:.||
Mouse     1 MASSSD------SEDDSV-MAVDQEETALEGTMEQ---DEDPHPVLEVEETRHNRSMSELPEEVL 55

  Fly   159 NVFLS--SDKQQSQMAGQIPMYAFQPLRLVK-----C-------------QYRDKHIP-GGFPLA 202
            ...||  |..|:.:.|.   :...|..||:|     |             |:..:..| .|.|:.
Mouse    56 EYILSFLSPYQEHKTAA---LVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPIT 117

  Fly   203 -RSGHR--IIASNSHLYSLGGYNPRSAMSASRHGRCLLFQELWSYNFATRTWRLELNAGNAANMP 264
             |..|.  ...:|..:|..||....|..:|        |.:||..:..::.|...|.:|   :.|
Mouse   118 QRFSHSACYYDANQSMYVFGGCTQSSCNAA--------FNDLWRLDLNSKEWIRPLASG---SYP 171

  Fly   265 VELASNALTIHNNVLISHGG----TGYP-------FGVSCSNDCYVYRTASAGATPGVD----RL 314
            ...|...|.::.::|:..||    :.||       |     ::.:.|       :|..:    .:
Mouse   172 SPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFF-----DEIHTY-------SPSKNWWNCIV 224

  Fly   315 QVKGDLPTAQYGPGIVIHKHFLYTIGGTTGF-DYTCDVYRLDLRTGIWENVYISRPEMRDDPEGR 378
            ...|..|.|.:...::..|..::  ||:.|. ..:.:|:.|||....|....||.|.  ..|.|.
Mouse   225 TTHGPPPMAGHSSCVIGDKMIVF--GGSLGSRQMSNEVWVLDLEQWAWSKPNISGPS--PHPRGG 285

  Fly   379 YRHEVVYDGKHIFVLGG 395
             :.::|.|...:.:|||
Mouse   286 -QSQIVIDDTTLLILGG 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slim	NP_523782.1	NanM	197..516	CDD:442289	49/218 (22%)
		KELCH repeat	203..263	CDD:276965	14/61 (23%)
		KELCH repeat	267..321	CDD:276965	11/68 (16%)
		KELCH repeat	324..364	CDD:276965	9/40 (23%)
		KELCH repeat	442..495	CDD:276965
Fbxo42	NP_766106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		14/42 (33%)
		F-box_FBXO42	47..84	CDD:438882	12/39 (31%)
		NanM	110..>321	CDD:442289	50/220 (23%)
		KELCH repeat	119..168	CDD:276965	13/56 (23%)
		Kelch 1	132..184		14/62 (23%)
		KELCH repeat	174..229	CDD:276965	10/66 (15%)
		Kelch 2	186..242		11/67 (16%)
		KELCH repeat	232..271	CDD:276965	9/40 (23%)
		Kelch 3	244..293		14/53 (26%)
		Kelch 4	295..342		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	361..452
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	570..632