Protein Alignment slim and Hcf

DIOPT Version :10

• Sequence 1: NP_523782.1
• Gene: slim / 37121
• FlyBaseID: FBgn0261477
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: XP_061507156.1
• Gene: Hcf / 1278452
• VectorBaseID: AGAMI1_010556
• Length: 1952
• Species: Anopheles gambiae
• Alignment Length: 379
• Identity: 83/379 - (21%)
• Similarity: 117/379 - (30%)
• Gaps: 115/379 - (30%)

  Fly   197 GGFPLARSGHRIIASNSHLYSLGGYNPRSAMSASRHGRCLLFQELWSYNFATRTWRLELNAGNAA 261
            |..|..|.|||.:.....:...||.|..            :..||..||.||..|
Mosquito    34 GPQPRPRHGHRSVNIKELMVVFGGGNEG------------IVDELHVYNTATNQW---------- 76

  Fly   262 NMPVELASNALTIHNNVLISHGGTGYPFGVSCSNDCYVYRTASAGATPGVDRLQVKGDLPTAQYG 326
                                                ||..|              |||:|.....
Mosquito    77 ------------------------------------YVPAT--------------KGDVPPGCAA 91

  Fly   327 PGIVIHKHFLYTIGGTTGF-DYTCDVYRLDLRTGIWENVYISRPEMRDDPEGRYRHEVVYDGKHI 390
            .|.|:....:...||...: .|:.::|.|......|:.:....||....|..|..|.....|..|
Mosquito    92 YGFVVDGTRILVFGGMVEYGKYSNELYELQATKWEWKKLRPKPPESGPPPCRRLGHSFTLVGDKI 156

  Fly   391 FVLGGGTSHSVYDLQRIPAY-------NLEAN--CWDYFETYPDQRAADADDGNRGYPKPRKCFS 446
            ::.||..:.|......||.|       .::.|  .|:...|:.:.            |.||:..:
Mosquito   157 YLFGGLANESDDPKNNIPKYLNDLYILEIKNNQLQWEIPTTFGES------------PPPRESHT 209

  Fly   447 CVQ-HQSSTGDIEAFITGGLQGDFSTYFSDIWKLNLRTKHWYRIETA-ILPRPLYFHSAAHSDNG 509
            .|. :..........|.||:.|   ....|:|.|:..|..|.|..|: .||.|...||:....|.
Mosquito   210 AVSWYDKKQKKFWLVIYGGMSG---CRLGDLWLLDTDTMSWTRPRTSGPLPLPRSLHSSTLIGNR 271

  Fly   510 CMYVFGG----------IEYIDKEMRRRNDLYKMWMTVPKLSEMCWDAITYYND 553
             ||||||          :|..:||.:..|.|..:     .|..|.|:.:....|
Mosquito   272 -MYVFGGWVPLVLDDVKVEKHEKEWKCTNTLACL-----NLETMTWEELDLDTD 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slim	NP_523782.1	NanM	197..516	CDD:442289	72/330 (22%)
		KELCH repeat	203..263	CDD:276965	14/59 (24%)
		KELCH repeat	267..321	CDD:276965	6/53 (11%)
		KELCH repeat	324..364	CDD:276965	8/40 (20%)
		KELCH repeat	442..495	CDD:276965	13/54 (24%)
Hcf	XP_061507156.1	None