DRSC/TRiP Functional Genomics Resources

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Protein Alignment slim and KLHDC9

DIOPT Version :9

Sequence 1:NP_523782.1 Gene:slim / 37121 FlyBaseID:FBgn0261477 Length:609 Species:Drosophila melanogaster
Sequence 2:NP_689579.3 Gene:KLHDC9 / 126823 HGNCID:28489 Length:349 Species:Homo sapiens


Alignment Length:314 Identity:64/314 - (20%)
Similarity:93/314 - (29%) Gaps:111/314 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   283 GGTGYPFGVSCSNDCYVYRTASAGATPGVDRLQVKGDLPTAQYGPGIVIHKHFLYTIGGTTGFDY 347
            ||...|     |:|..|:..|...|.    ||..:|..|.:.: ....:...:|..:||..|...
Human    49 GGAREP-----SSDTVVFDPARGQAV----RLGARGSPPRSHH-DAAPVDGRWLCVVGGWDGSRR 103

  Fly   348 TCDVYRLDLRTGIWE---------------------------------------NVYISRPEMRD 373
            ...|..||...|:||                                       ..|.|...:|.
Human   104 LATVTALDTERGVWEAWTGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRL 168

  Fly   374 DPEGR---YRHEVVYDGKHIFVLGGGTS--------HSVYDLQRIPAYNLE----ANCWDYFETY 423
            ||..|   |:.|    |.|.....|..:        |..:.|......||.    |..|.:.:..
Human   169 DPSARTYCYKQE----GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK 229

  Fly   424 PD-----------QRAADADDGNRGYPKPRKCFSCVQHQSSTGDIEAFITGG--LQGDFSTYFSD 475
            .:           .|...:..|::..|...:..||    |..|.. |.:.||  |.....|..:|
Human   230 EEPPVAPHLMEQLARLVSSGQGSQKGPHGLRHHSC----SVVGPF-AVLFGGETLTRARDTICND 289

  Fly   476 IWKLNLRTKHWYRIETAILPRPLYFHSAAHSDNG--------C-----MYVFGG 516
            ::..:.||.           .||:||... :|.|        |     :|:.||
Human   290 LYIYDTRTS-----------PPLWFHFPC-ADRGMKRMGHRTCLWNDQLYLVGG 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slimNP_523782.1 KELCH repeat 203..263 CDD:276965
KELCH repeat 267..321 CDD:276965 11/37 (30%)
KELCH repeat 324..364 CDD:276965 10/78 (13%)
Kelch_1 325..372 CDD:279660 12/85 (14%)
Kelch_4 441..492 CDD:290154 12/52 (23%)
KELCH repeat 442..495 CDD:276965 12/54 (22%)
KLHDC9NP_689579.3 KELCH repeat 28..76 CDD:276965 10/35 (29%)
Kelch_3 37..85 CDD:290151 12/45 (27%)
Kelch 1 39..89 12/49 (24%)
Kelch_1 78..118 CDD:279660 9/40 (23%)
KELCH repeat 79..118 CDD:276965 8/39 (21%)
Kelch 2 91..137 10/45 (22%)
KELCH repeat 187..239 CDD:276965 7/51 (14%)
KELCH repeat 259..311 CDD:276965 17/68 (25%)
Kelch 3 325..349 3/7 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0379
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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